Clinical profile of patients presented with esophageal carcinoma in tertiary care teaching medical college of Gujarat, India

Abstract

Background: Esophageal cancer is associated with multiple risk factors and associated with poor prognosis. Incidence of Esophageal cancer is increases now a days and it became a sixth leading cause of cancer related death in world. The purpose of this study was to know the clinical profile of patients of esophageal cancer in a tertiary care teaching hospital of Gujrat, India.Methods: This is a retrospective hospital record based study for a period of 2015 to 2018 in which 103 patients with endoscopic biopsy confirmed cases of esophageal cancer were analyzed for clinical profile.Results: Esophageal cancer was most common in low socioeconomic men (66%) of 5th decades (26.21%) associated with tobacco chewing (64.07%) as a major risk factor and dysphagia (86.76%) as most common presenting feature. Most common type and involvement were sqamous type (72.81%) and distal third (50.48%) part of the esophagus respectively.Conclusions: Primordial prevention and screening of patients may decrease mortality related to esophageal carcinoma.

Clinical profile of patients with esophageal carcinoma: A multicentric study from North India

“…In our study majority (approximately 70%) of patients were in the age group of 50 years and above. [12,13] Similar finding were reported by study conducted by Kumar S et al where nearly three fourth of patients belongs to age group of above 50 yrs.…”

“…Approximately 50% cases of esophageal cancers are ADCs in Western countries in contrast, SCC continues to be the dominant type in other areas of the world, especially in Asia. [18] Similar findings were reported by Kumar et al, [12] from Gujarat, India where 75.8% of cases had SCC.…”

“…Similarly, studies performed by other researchers also reported dysphagia to be one of the most common presenting symptom which was seen in upto 80% of cases of oesophageal carcinoma. [12,14,15] Loss of weight was 2nd most common presentation (26.4%) in our study subjects which was closely followed by vomiting & odynophagia. Other studies have also reported loss weight was 2 nd most common presentation but it was present in 60-70 % of the cases.…”

“…This finding was similar to results of other studies from india where distal one third was most common site of oesophageal carcinoma. [12,17] On histopathological diagnosis, SCC (squamaous cell carcinoma) was seen in majority (80%) of patients while Adenocarcinoma (ADC) was seen in only 20 % cases. Approximately 50% cases of esophageal cancers are ADCs in Western countries in contrast, SCC continues to be the dominant type in other areas of the world, especially in Asia.…”

Upper Gastrointestinal Cancers in Rwanda: Epidemiological, Clinical and Histopathological Features in Patients Presenting to a Tertiary Referral Hospital

“…Dysphagia and loss of weight were common manifestations of esophageal cancers in our cohort, similar to findings by Mchembe et al in Tanzania [32] and Gibbs [37]. A study of esophageal cancer at a tertiary care teaching college in India al found that dysphagia was the most common symptom (86%) [38].…”