Clinical profiles of patients with optic neuritis at the Ophthalmological Department of Chiba University

Abstract

Objective: To determine the clinical features of 272 patients who were diagnosed with optic neuritis at an ophthalmological clinic in Japan. Methods: We reviewed the records of patients examined between January 1977 and late June 1999. Results: The ratio of women to men was 1.7 : 1. The mean age at onset was 35 years and 80.5% were unilateral. The most frequent complaint was a vision decrease in 82.4%. The disc appeared normal in 38.5%. The median visual acuity at onset was 0.1; it was 1.0 at the recovered stage. The mean time required for visual recovery was 92.3 days from the onset. The most common known cause of optic neuritis was multiple sclerosis (MS)(22.8%). The recurrence rate was 22.0% and the mean number of recurrences was 2.9. The time for the development of disc pallor was 124.8 days. Conclusions: We found no racial difference in the incidence of MS as has been reported between Caucasians and Japanese.

Demographic pattern and clinical characteristics of optic neuritis in a tertiary eye care centre

“…In our study female predominance was seen similar to the study in Japan (Suehiro et al, 2002) and China (Zhang et al, 2008). However male predominance was seen in previous studies from Nepal (Das H et al, 2010;Shrestha R et al, 2007).…”

“…In our study 58% had painful ocular movement almost similar to Indian study -66% (Saxena et al, 2010), but more than in the studies from China-42.9% (Zhang et al, 2008), Chandigarh-33.4% (Jain et al, 1980), Eastern Nepal-33.33% (Das H et al, 2010) and Japan-17.6% (Suehiro et al, 2002). …”

“…Unilateral optic neuritis was more than bilateral optic neuritis similar to the study in India (Saxena et al, 2010), China (Zhang et al , 2008) and Japan (Suehiro et al, 2002). In contradiction study from Eastern Nepal (Das H et al, 2010) showed more cases of bilateral optic neuritis and another centre in Kathmandu showed equal number of unilateral and bilateral cases (Shrestha R et al, 2007).…”

“…None of the study cases were diagnosed as multiple sclerosis similar to studies from China (Zhang et al, 2008) and India (Jain et al, 1980). In contradictory study from Japan (Suehiro et al, 2002) reported 22.8% cases of optic neuritis associated with multiple sclerosis. Another Indian study (Saxena et al, 2010) reported 2 cases of multiple sclerosis.…”

Clinical Features and Visual outcome in Acute and Recurrent Case of Optic Neuritis.

“…In study done by I-H. Wang et al 7 in Taiwan, 76.7% of the patients were female. In ONTT too there was female preponderance i.e 77.2% 6 in Japan (17.6%). In ONTT8 92% of their patients had ocular pain.…”