Clinical, Radiographic, and Morphometric Risk Factors for Adjacent and Remote Vertebral Compression Fractures Over a Minimum Follow-up of 4 Years After Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures: Novel Three-dimensional Voxel-Based Morphometric Analysis

Lee, Hong-Jae; Park, Jinah; Lee, Il-Woo; Yi, Jin-Seok; Kim, Sang Woo

doi:10.1016/j.wneu.2019.01.020

Cited by 29 publications

(87 citation statements)

References 46 publications

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“…A 2019 report revealed that the risk factors for AVCF after VP include BMD, preoperative compression ratio, preoperative sagittal index, intradiscal cement leakage, and large cement volume-to-vertebral body ratio as per univariate analysis. [ 44 ] Significant risk factors as per multivariate analysis were BMD and intradiscal cement leakage. The lack of significant differences in the ratio of AVCF may be due to a lack of such differences in the ratio of BMD and intradiscal cement leakage between the 2 groups.…”

Section: Discussionmentioning

confidence: 99%

Comparison of efficacies of unipedicular kyphoplasty and bipedicular kyphoplasty for treatment of single-level osteoporotic vertebral compression fractures

et al. 2020

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Section: Discussionmentioning

confidence: 99%

Comparison of efficacies of unipedicular kyphoplasty and bipedicular kyphoplasty for treatment of single-level osteoporotic vertebral compression fractures

et al. 2020

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“…10,14,17 Pooling these studies with random-effects model showed that IVC could T-score data was provided by 9 studies. 10,12,[14][15][16]18,21,22,25 Patients with lower T-score were statistical more likely to develop AVF (SMD ¼ À0.589; 95%CI, À0.812 to À0.366; P ¼ 0.000) under the random-effects model of meta-analysis ( Figure 6). Moderate statistical heterogeneity existed between the studies (P ¼ 0.019; I 2 ¼ 56.3%).…”

Section: Pooled Analysis Of Preoperative Risk Factorsmentioning

confidence: 99%

What Are the Risk Factors for Adjacent Vertebral Fracture After Vertebral Augmentation? A Meta-Analysis of Published Studies

Zhang

Wang

Zhang

et al. 2020

Global Spine Journal

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Study Design: Meta-analysis. Objectives: To provide up-to-date evidence-based outcomes for the incidence and risk factors of adjacent vertebral fracture (AVF) after the vertebral augmentation. Methods: The MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials were searched for studies assessing the risk factors of adjacent vertebral fracture after vertebral augmentation until June 2020. The AVF incidence and factors potentially affecting AVF were extracted and pooled. Results: A total of 16 studies, encompassing 2549 patients were included in the meta-analysis. The pooled incidence of AVF was 14% after vertebral augmentation. Female, lower T-score, thoracolumbar junction fracture, intravertebral cleft, more injected cement volume, intradiscal cement leakage significantly increased the risk of AVF. Age, body mass index, steroid medication, Cobb angle change, postoperative Cobb angle showed no significant association with AVF. Conclusions: Identifying the risk factors of AVF can facilitate prevention strategy to avoid the AVF. Female, T-score, thoracolumbar junction fracture, intravertebral cleft, more cement volume, and intradiscal cement leakage increased the risk of AVF.

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“…In addition, there is some controversy among authors regarding a possible relationship between the realization of PVP and the appearance over time of new FV [31][32][33] . This reason justifies the analysis, such as the one we present here, where post-surgery follow-ups are recorded much longer over time.…”

Section: Originalsmentioning

confidence: 99%

“…In the 7 cases presented, the patients presented stability in the intervened vertebral bodies at the level of the anterior, middle and posterior walls with 15 or more years elapsed from the time of surgery. There are some published data that associate changes in the angulation of the lamellar plate after VF as a risk factor in the appea-rance of new VF 31,34 . In our series of patients analyzed, there were no clinically significant differences in this angulation after 15 or more years post-op which could justify, together with other factors such as maintenance of osteoporotic treatment, that these patients have not suffered new VF in adjacent segments.…”

Section: Originalsmentioning

confidence: 99%

Eficacia y seguridad a largo plazo del polimetilmetacrilato (PMMA) en pacientes osteoporóticos tratados mediante vertebroplastia percutánea

López‐Herradón

Piñera

Tomé³

et al. 2019

Rev Osteoporos Metab Miner

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Objetive: Currently, there are limited data on the long-term influence of polymethylmethacrylate (PMMA) on the integrity of vertebral bodies after percutaneous vertebroplasty (PVP). Interesting investigation is being carried out into the possible relationship between this technique and the appearance over time of osteolytic phenomena or cement fragmentation in the intervened vertebrae. The objective of our study was to investigate whether there is a loss of effectiveness and/or safety of PVP with PMMA in the long term. Material and methods: X-rays were analyzed of intervened patients corresponding to the immediate post-operative and the most recent radiological study (PVP more than 15 years previous). With both radiological studies, we describe: the height of the vertebral body, the angulation of lamellar plates and osteolytic presence around the cement over time. Results: A total of 7 patients operated by PVP with PMMA 15 or more years earlier agreed to have a new radiograph in our center. After the analysis of their post-operative images (immediate and 15 or more years after surgery), no loss of height of the cemented vertebral body, differences in angulation in the lamellar plates, presence of osteolysis around the vertebrae was observed in any of the involved vertebrae cement or fragmentation of the injected PMMA. Conclusion: PMMA injected into the vertebral body remains stable over time (more than 15 years). There are no changes in the bone-PMMA interface, osteolysis and/or changes in the height of the vertebral bodies in the cases analyzed.

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Clinical, Radiographic, and Morphometric Risk Factors for Adjacent and Remote Vertebral Compression Fractures Over a Minimum Follow-up of 4 Years After Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures: Novel Three-dimensional Voxel-Based Morphometric Analysis

Cited by 29 publications

References 46 publications

Comparison of efficacies of unipedicular kyphoplasty and bipedicular kyphoplasty for treatment of single-level osteoporotic vertebral compression fractures

Comparison of efficacies of unipedicular kyphoplasty and bipedicular kyphoplasty for treatment of single-level osteoporotic vertebral compression fractures

What Are the Risk Factors for Adjacent Vertebral Fracture After Vertebral Augmentation? A Meta-Analysis of Published Studies

Eficacia y seguridad a largo plazo del polimetilmetacrilato (PMMA) en pacientes osteoporóticos tratados mediante vertebroplastia percutánea

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