Clinical, Radiological Features and Outcome of COVID-19 patients in a Secondary Hospital in Jakarta, Indonesia

Hafiz, Muhammad Yusuf; Icksan, Aziza Ghanie; Harlivasari, Annisa Dian; Aulia, Rizky; Susanti, Febrina; Eldinia, Lourisa

doi:10.3855/jidc.12911

Cited by 15 publications

(12 citation statements)

References 16 publications

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“…We observed that the males comprised an overwhelming majority (82.3%) of our patients This is similar to the data from other South Asian countries like India, Pakistan, Bangladesh, and Iran where the males comprised 60 to 90% of the admitted COVID-19 patients [9][10][11][12]. The male preponderance among the hospitalized patients was less pronounced in countries like the US, UK,China and Indonesia [13][14][15][16].One possible reason for this overwhelming male majority is that most of the COVID-19 patients in our study were migrant workers, and it is usually the adult males who go abroad for work. Another reason could be that the Nepalese society is highly patriarchal and are expected to earn a living for the family while most of the females are limited to their homes as housewives [17], thus limiting their exposure.…”

Section: Discussionsupporting

confidence: 88%

Characteristics and outcomes of hospitalized adults with COVID-19 in Nepal: a multicenter, prospective cohort study

Chaudhary¹,

Singh

Paudel³

et al. 2020

Preprint

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Introduction There is limited data on clinical course and outcomes of hospitalized adults with COVID-19 in Nepal. Thus, it is imperative to characterize the features of this disease in the domestic context. Methodology We identified all adult patients with laboratory-confirmed COVID-19 admitted to five different hospitals in Nepal from June 15 to July 15, 2020. We collected epidemiological, socio-cultural and clinicopathologic data, and stratified the patients based on their symptom status. Results The study included 220 patients with an overall median age of 31.5 (25-37) years, and 181 (82.3%) were males. 159 (72.3%) were asymptomatic, and 163 (74.1%) were imported cases. Of 217 patients with the available data, 110 (50.7%) reported their annual household income less than 2000 US dollars, and 122 (56.2%) practiced Pranayama (yogic rhythmic breathing techniques) regularly. Eight patients (3.6%) required supplemental oxygen and two patients (0.9%) died. None of the patients who practiced Pranayama regularly required supplemental oxygen. Compared to asymptomatic patients, symptomatic patients had greater proportion of females (31.1% vs. 12.6%, p=0.001), imported cases (85.2% vs. 69.8%, p=0.02), illiterates (26.8% vs. 12.1%, p=0.01), alcohol users (43.3% vs. 24.5%, p=0.01), patients feeling stigmatized by society (45.8% vs. 22.6%, p=0.001), and had higher platelet count (253 x 10^9/L vs. 185 x10^9/L, p=0.02). Conclusions Most cases were imported, asymptomatic young males, with very few deaths. Pranayama practice was associated with protection against severe COVID-19, but more data is needed to substantiate this. The association of platelets count with symptom status in the Nepalese population needs further exploration.

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Section: Discussionsupporting

confidence: 88%

Characteristics and outcomes of hospitalized adults with COVID-19 in Nepal: a multicenter, prospective cohort study

Chaudhary¹,

Singh

Paudel³

et al. 2020

Preprint

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“…The hematologic abnormalities that were found in this study were leukocytosis (18%), neutrophilia (20%), and lymphopenia (28%). This finding is in line with a study conducted by Hafiz et al (2020) of 30 COVID-19 patients at a secondary referral hospital in Jakarta, that leukocytosis was found in 16.7% of patients, neutrophilia was found in 76.9%, and lymphopenia was found in 70% of patients. The literature has linked leukocytosis, neutrophilia, and lymphopenia with severe COVID-19 .…”

Section: The Laboratory Findings On Covid-19supporting

confidence: 92%

Clinical Characteristics of Coronavirus Disease 2019 in Dr. Agoesdjam Regional Public Hospital, Ketapang, West Kalimantan, Indonesia

Willim¹,

Cristianto²,

Sihombing³

et al. 2020

J EPIDEMIOL PUBLIC HEALTH

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Background: Coronavirus disease 2019 is a new pandemic caused by SARS-CoV-2 infection. COVID-19 has spread to almost all countries with increasing cases, including Indonesia. Data on the clinical characteristics of COVID-19 in Indonesia is still limited. This study aimed to determine the clinical characteristics of COVID-19. Subjects and Method: This study was a descriptive study with a retrospective design conducted in Dr. Agoesdjam Regional Public Hospital. The data were obtained from the medical records of all patients with confirmed COVID-19 from April 1 to July 31, 2020. There were 50 patients as the sample of the study. The data collected were demographics, exposure history, smoking status, comorbidities, clinical symptoms, outcomes, drug therapy, laboratory, chest X-ray, and electrocardiography (ECG). This study used descriptive statistics. Results: The patients on average aged 34.8 years (Mean= 34.8; SD= 14.0). Patients were dominated by the 30-39 years age group (28%) and men (56%). More than a third of patients (36%) were health workers. Most of the cases were local transmission (78%). Almost half of the patients (48%) were smokers. The most common comorbid was hypertension (12%). The dominant clinical symptoms were cough (34%), dyspnea (14%), and fever (10%). More than half of the patients (58%) were asymptomatic. The mortality rate was 2%. All patients received supportive therapy. Azithromycin was the most potential drug given (30%). Abnormal laboratory findings included leukocytosis (18%), neutrophilia (20%), lymphopenia (28%), elevated erythrocyte sedimentation rate (32%), alanine aminotransferase (36%), and aspartate aminotransferase (18%). Abnormal chest X-ray was found in 10% of patients. Among the 22 patients who were examined on the ECG, the abnormal figures were found in 40.9% of patients with non-specific findings. Conclusion:The COVID-19 patients in this study are dominated by young adults and men. Asymptomatic and mild symptoms are more common. The symptoms that are often complained of are coughing, dyspnea, and fever. The common laboratory abnormalities were leucocytosis, neutrophilia, lymphopenia, elevated erythrocyte sedimentation rate, and elevated liver enzymes. The most common chest X-ray abnormality is consolidation. During the COVID-19 pandemic, prevention and control are the main priorities. In addition, the level of public awareness must be raised.

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“…Previously reported studies among patients with COVID-19 have stated predominance of older age and male sex, particularly in hospitalized patients. 2,4,5,[12][13][14][15][16][17][18][19][20][21][22] Similarly, 55.5% of our patients were male and the median age was 57.…”

Section: Discussionmentioning

confidence: 97%

“…Older age, male sex and comorbidities were significantly associated with the severity of the disease and mortality. 2,4,5,[13][14][15][16][17][18][19][20][21][22][23] It has been reported that 13-73.4% of the patients had comorbidities. [13][14][15]23 58.7% of our patients had at least one accompanying comorbidity.…”

Section: Discussionmentioning

confidence: 99%

“…The rate of patients who needed intensive care has been reported to be 5-15.7% in different studies. 2,3,18,22,25,41,42 Mortality varies from 2.08% to 78% in patients with COVID-19 disease 12,14,15,21,24,41,42 , and from 1.4% to 72% among ICU patients with COVID-19. 3,4,16,17,27 In the studies conducted in our country, mortality rates between 2.08 and 10.5% 26,27,41,42 have been reported.…”

Section: Discussionmentioning

confidence: 99%

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Assessment and management of the SARS-CoV-2 infection: A secondary center experience

Yardımcı

Ergen

Yıldız

et al. 2021

Preprint

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Background: The aim of the study was to evaluate the management and outcomes of the patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a secondary hospital. Methods: A total of 699 hospitalized patients who had positive rRT-PCR for SARS-CoV-2 and/or typical findings of COVID-19 at chest computed tomography (CT) were enrolled in this study. Demographics, comorbities, initial laboratory tests on admission, treatment modalities, complications and outcomes were evaluated retrospectively. Results: The mean age was 57.0±15.6 (range:16-94 years), and male:female ratio was 1.24. 58.7% of the patients had at least one underlying comorbidity, the most common was hypertension. 72.8% of the patients had positive RT-PCR. 18.1% of the patients had lymphopenia, 35.7% hyperferritinemia, 58.3% increased lactate dehydrogenase, and 58.5% increased D-dimer. Chest CT revealed moderate and severe stage in 57.9% of the patients, and bilateral lung involvement in 78.7%. Hydroxychloroquine was given to 37.2% and favipiravir 67.1% of the patients. No significant difference was observed between treatment groups in terms of mortality (P=0.487). 5.8% of the patients were transferred to the ICU, of whom 75.6% were needed non-invasive and 36.5% invasive mechanical ventilation. The overall case fatality rate was 0.9. Conclusions: Older age, male sex, low lymphocyte count, CT findings including bilateral involvement and severe stage were significantly associated with poor prognosis and mortality.

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Clinical, Radiological Features and Outcome of COVID-19 patients in a Secondary Hospital in Jakarta, Indonesia

Cited by 15 publications

References 16 publications

Characteristics and outcomes of hospitalized adults with COVID-19 in Nepal: a multicenter, prospective cohort study

Characteristics and outcomes of hospitalized adults with COVID-19 in Nepal: a multicenter, prospective cohort study

Clinical Characteristics of Coronavirus Disease 2019 in Dr. Agoesdjam Regional Public Hospital, Ketapang, West Kalimantan, Indonesia

Assessment and management of the SARS-CoV-2 infection: A secondary center experience

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