Clinical results of pulsed signal therapy on patellofemoral syndrome with patellar chondropathy

Gobbi, Riccardo Gomes; Silva, Adriana Lucia Pastore e; Demange, Marco Kawamura; Pécora, José Ricardo; Espregueira-Mendes, João; Camanho, Gilberto Luís

doi:10.1002/bem.22172

Cited by 2 publications

(1 citation statement)

References 28 publications

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“…TIO is caused by hypophosphatemia and bone mineralization disorders associated with tumors, but rarely shows obvious clinical symptoms. Even if the patient has reduced blood phosphorus, there is no specificity for clinically distinguishing the patient's lesion (8,9). The majority of TIO patients suffer from severe systemic symptoms, which significantly reduce the quality of life.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic value of 68Ga-DOTA-TATE PET/CT imaging for tumor- induced osteomalacia

Zhang

Huang

et al. 2020

Ann Palliat Med

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Background: Tumor-induced osteomalacia (TIO) is often misdiagnosed as hypophosphatemia that is not valued. The aim of this study was to analyze the diagnostic value of 68 Ga-DOTA-TATE PET/CT imaging for TIO.Methods: Clinical data was retrospectively collected for 56 patients with suspected TIO at the Affiliated Hospital of Southwest Medical University between January 2016 and December 2019, where patients were examined by 68 Ga-DOTA-TATE PET/CT and 99m Tc-HYNIC-TOC SPECT. Based on the results of the patient's surgery, the diagnostic efficacy of the two imaging techniques on TIO were analyzed.Results: Of the 56 patients, 41 were diagnosed with TIO, with phosphorus levels ranging from 0.25 to 0.75 mmol/L. The remaining 15 patients were non-TIO. Results of 99m Tc-HYNIC-TOC SPECT showed 33 cases were positive, with a diagnostic sensitivity, specificity, and accuracy of 58.54%, 86.67%, and 66.07%, respectively. Results of 68 Ga-DOTA-TATE PET/CT imaging showed 46 cases were positive, with a diagnostic sensitivity, specificity, and accuracy of 95.13%, 60.00%, 71.43%, respectively. The average tumor size with 68 Ga-DOTA-TATE PET/CT imaging was 2.58±1.71 cm. The lesions of 41 patients involved bone and soft tissue, while 18 patients showed osteolytic bone destruction. Distribution was mainly under the skin, followed by intermuscular space, and cortex of bone. Compared with muscle density, the lesions showed uniformly or slightly lower density nodules. Using 99m Tc-HYNIC-TOC SPECT, the planar imaging of 30 patients showed that radioactive uptake increased at the early stage, and it can be accurately positioned on the SPECT imaging. Conclusions:The 68 Ga-DOTA-TATE PET/CT imaging demonstrated high accuracy in the diagnosis of TIO and detected small lesions, which could provide more comprehensive information for clinicians, and provide a reference value for the treatment and prognosis of patients.

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Section: Discussionmentioning

confidence: 99%

Diagnostic value of 68Ga-DOTA-TATE PET/CT imaging for tumor- induced osteomalacia

Zhang

Huang

et al. 2020

Ann Palliat Med

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Six Treatments Have Positive Effects at 3 Months for People With Patellofemoral Pain: A Systematic Review With Meta-analysis

Neal¹,

Bartholomew²,

Barton³

et al. 2022

Journal of Orthopaedic & Sports Physical Therapy

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OBJECTIVE: To determine the effects of nonsurgical treatments on pain and function in people with patellofemoral pain (PFP). DESIGN: Systematic review with meta-analysis. LITERATURE SEARCH: We searched MEDLINE, Web of Science, and Scopus databases from their inception until May 2022 for interventional randomized controlled trials (RCTs) in people with PFP. STUDY SELECTION CRITERIA: We included RCTs that were scored ≥7 on the PEDro scale. DATA SYNTHESIS: We extracted homogenous pain and function data at short- (≤3 months), medium- (>3 to ≤12 months) and long-term (>12 months) follow-up. Interventions demonstrated primary efficacy if outcomes were superior to sham, placebo, or wait-and-see control. Interventions demonstrated secondary efficacy if outcomes were superior to an intervention with primary efficacy. RESULTS: We included 65 RCTs. Four interventions demonstrated short-term primary efficacy: knee-targeted exercise therapy for pain (standardized mean difference [SMD], 1.16; 95% CI: 0.66, 1.66) and function (SMD, 1.19; 95% CI: 0.51, 1.88), combined interventions for pain (SMD, 0.79; 95% CI: 0.26, 1.29) and function (SMD, 0.98; 95% CI: 0.47, 1.49), foot orthoses for global rating of change (OR = 4.31; 95% CI: 1.48, 12.56), and lower-quadrant manual therapy for function (SMD, 2.30; 95% CI: 1.60, 3.00). Two interventions demonstrated short-term secondary efficacy compared to knee-targeted exercise therapy: hip-and-knee-targeted exercise therapy for pain (SMD, 1.02; 95% CI: 0.58, 1.46) and function (SMD, 1.03; 95% CI: 0.61, 1.45), and knee-targeted exercise therapy and perineural dextrose injection for pain (SMD, 1.34; 95% CI: 0.72, 1.95) and function (SMD, 1.21; 95% CI: 0.60, 1.82). CONCLUSIONS: Six interventions had positive effects at 3 months for people with PFP, with no intervention adequately tested beyond this time point. J Orthop Sports Phys Ther 2022;52(11):750–768. Epub: 8 September 2022. doi:10.2519/jospt.2022.11359

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Clinical results of pulsed signal therapy on patellofemoral syndrome with patellar chondropathy

Cited by 2 publications

References 28 publications

Diagnostic value of 68Ga-DOTA-TATE PET/CT imaging for tumor- induced osteomalacia

Diagnostic value of 68Ga-DOTA-TATE PET/CT imaging for tumor- induced osteomalacia

Six Treatments Have Positive Effects at 3 Months for People With Patellofemoral Pain: A Systematic Review With Meta-analysis

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