“…Of note, upsloping STD is not a specific marker of ischemia as it is often associated with increased heart rate (Desai, Crugnale, Mondeau, Helin, & Mannting, 2002; Polizos & Ellestad, 2006) and can even be found in myocarditis (García‐Izquierdo et al., 2018) and post‐supraventricular tachycardia (Khalid & Birnbaum, 2016). Upsloping STD in patients with chest pain without tachycardia, with concomitant tall symmetrical T waves and even pathological Q wave or equivalent is the typical feature for patients with ongoing ischemia, while upsloping STD with tachycardia in asymptomatic or atypical cases is the characteristic for patients, where the background factor is other than ischemia (Alam, Nikus, Fiol, Bayes de Luna, & Birnbaum, 2019; Khalid & Birnbaum, 2016).…”