Breast cancer continues to be a substantial worldwide health concern, affecting millions of individuals each year; this emphasizes the critical nature of early detection in order to enhance patient prognoses. The present study aims to assess the classification performance of three convolutional neural network (CNN) architectures-visual geometry group 19 (VGG19), AlexNet, and residual network 50 (ResNet50)-with respect to breast cancer detection in medical images. Thorough assessments, encompassing metrics such as accuracy, precision, recall, and F-score, were undertaken to evaluate the diagnostic performance of the models. ResNet50 consistently outperforms other models, as evidenced by its highest accuracy and F-score. The research highlights the significant importance of carefully choosing suitable architectures for medical image analysis, with a specific focus on the detection of breast cancer. In addition, it demonstrates the capacity of deep learning models, such as ResNet50, to improve the diagnosis of breast cancer with exceptional precision and sensitivity, which is critical for reducing the occurrence of false positives and negatives in clinical environments. In addition, computational efficiency is taken into account; AlexNet is recognized as the most efficient model, which is advantageous in environments with limited resources. This study advances medical image processing by demonstrating the potential of CNNs in the detection of breast cancer. The results of this study establish a fundamental basis for sub- sequent inquiries and suggest approaches to improve timely detection and treatment, which will ultimately be advantageous for both patients and healthcare professionals.