Clinical Treatment of Gastroesophageal Reflux Disease: What Do the Latest Studies Avoid?

Abstract

of more potent prokinetic agents and acid secretion inhibitors, the role of surgery as a definitive therapeutic weapon for complicated reflux has been questioned. Conclusions: Surgical treatment, when properly indicated, tends to be a definitive way to resolve the typical and atypical symptoms of GERD. On the other hand, considering the multidimensional etiopathogenesis of the disease, clinical treatment is still the best alternative to start with. It is understandable that the adjustment of doses, the association of classes, the combination with behavioral measures and the due adherence by the patient are presented as determinant measures for the therapeutic success, being able to avoid a surgical approach in most cases.