2007
DOI: 10.1016/j.athoracsur.2006.08.042
|View full text |Cite
|
Sign up to set email alerts
|

Clinical Value of Serum Cytokeratin 19 Fragment and Sialyl-Lewis X in Non-Small Cell Lung Cancer

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
21
1
1

Year Published

2007
2007
2018
2018

Publication Types

Select...
9

Relationship

2
7

Authors

Journals

citations
Cited by 32 publications
(23 citation statements)
references
References 28 publications
0
21
1
1
Order By: Relevance
“…We have reported that a combination of SLX and CYFRA21-1, using the diagnostic cut-off values, significantly contributed to the classification of 272 patients with NSCLC [48]. In this study, the combination of serum SLX and CYFRA21-1, using prognostic cut-off values, should also significantly contribute to the classification of stage 1 NSCLC patients.…”
Section: Discussionmentioning
confidence: 79%
“…We have reported that a combination of SLX and CYFRA21-1, using the diagnostic cut-off values, significantly contributed to the classification of 272 patients with NSCLC [48]. In this study, the combination of serum SLX and CYFRA21-1, using prognostic cut-off values, should also significantly contribute to the classification of stage 1 NSCLC patients.…”
Section: Discussionmentioning
confidence: 79%
“…Our findings might indicate that the higher frequency of Lewis-negative genotype could result in the lack of Lewis antigen in epithelial tissues and/or tumor cells, resulting in decreased adhesiveness of breast tumor cells, which seems to be essential for the development of malignant tumors in vivo. Patients with non-small cell lung cancer and with the absence of sialyl-Lewis x antigen were TNM stage I, and their relative risk was 6.10 lower than in patients with the Lewis antigen [54]. However, tumor cells with absent or low Lewis antigen expression could be able to escape immunosurveillance mediated by natural killer (NK) cells since previous studies have demonstrated that NK cells attack melanoma tumor cells expressing high levels of sialyl-Lewis x [55].…”
Section: Discussionmentioning
confidence: 95%
“…The commonly used cancer biomarkers are as follows: CEA, AFP, CA125, CA19-9, CA15-3, Ferritin, β 2 microglobulin, Cyfra21-1 and PSA [5][6][7][8][9][10][11][12][13][14][15]. The results of Table 1 Positive detection rates of CA215 and other cancer biomarkers individually (upper line) or their combinations (CA215 combined with known markers, lower line) such extensive analyses are summarized together with CA215 in Table 1.…”
Section: Serum Levels Of Other Cancer Biomarkers Among Cancer Patientsmentioning
confidence: 96%