Clinical value of spectral CT in diagnosis of negative gallstones and common bile duct stones

Li, Huanguo; He, Dong; Lao, Qun; Chen, Xingcan; Miao, Liyun; Yin, Bingxin; Zhao, Kaiyu; Wang, Rui; Chen, Long-Xia

doi:10.1007/s00261-015-0387-y

Cited by 21 publications

(7 citation statements)

References 26 publications

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“…Spectral CT scaning can simultaneously yield mixed energy and monochromatic-energy images (40–140 keV) [ 10 , 11 , 12 , 13 ]. In general, the low energy levels with high contrast and high noise.…”

Section: Resultsmentioning

confidence: 99%

Effects of low-dose energy spectrum scanning combined with adaptive statistical iterative reconstruction on the quality of imaging in Budd-Chiari syndrome

Chang

Sun

et al. 2018

PLoS ONE

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ObjectiveTo assess the quality and diagnostic accuracy of monochromatic images combined with adaptive statistical iterative reconstruction (ASIR) performed via spectral computed tomography (CT) in patients with Budd-Chiari syndrome (BCS).MethodsSixty-two patients with BCS underwent pectral CT with upper abdominal two-phase contrast-enhanced scanning to generate a 60keV monochromatic energy level combined with ASIR (ranging from 0% -100%) during the portal venous phase (PVP) and the hepatic venous phase (HVP). One-way ANOVA was used to compare vessel-to-liver contrast-to-noise ratio (CNR) for the portal vein (PV), hepatic vein (HV), and inferior vena cava (IVC). Subjective evaluations of the images in the three groups were conducted by image quality assessors and compared via Kruskal-Wallis H test.ResultsThe CNR values of the PV trunk, HV, IVC, liver parenchyma and pancreas were within ASIR (ranging from 0% - 100%) weight, and the difference were statistically significant (p <0.05). The highest overall image score was distributed at 50% ASIR weight value. Higher CNR values of HV, hepatic parenchyma and pancreas were obtained in the IVC type than in mixed and HV types (respective p values = 0.035, 0.019 and 0.042). Higher CNR values of the IVC were obtained in the HV type than in mixed and IVC types (p = 0.032). The CNR value of the IVC in the mixed type was less than that of the HV type (p = 0.028). The CNR values of the HV and liver parenchyma in mixed type were lower than those of the IVC type (p = 0.016 and 0.038, respectively). The CNR value of pancreas in IVC type was higher than that of the HV type (p = 0.037). The diagnostic value of CNR in patients with the IVC type was higher than that in patients with mixed and HV type, while the diagnostic value of CNR was found to be the lowest for the HV type (p = 0.043).ConclusionA monochromatic energy level of 60 keV with 50% ASIR can significantly improve image quality in cases of BCS.

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Section: Resultsmentioning

confidence: 99%

Effects of low-dose energy spectrum scanning combined with adaptive statistical iterative reconstruction on the quality of imaging in Budd-Chiari syndrome

Chang

Sun

et al. 2018

PLoS ONE

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“…Our results showed that each of the selected drugs had different X-ray absorption, thus facilitating their assessment in the gastrointestinal tract. These differences result in differences in image densities, which, in addition to their size and shape, should allow the differentiation of medicines from other potential foreign bodies in the gastrointestinal tract, e.g., stones [12][13][14] and bezoars [15][16][17][18]. The pills could easily be measured on abdominal CT images and could be compared with the attenuation and noise of typical medications, as listed in table 1, to narrow down the possible identity of the agent.…”

Section: Discussionmentioning

confidence: 99%

Computed tomography imaging for the characterisation of drugs with radiation density measurements and HU spectroscopy

Sieroń¹,

Steib²,

Suter³

et al. 2018

Swiss Med Wkly

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“…Dual-energy CT with virtual monoenergetic image analysis has been demonstrated to be helpful in the detection of noncalcified gallstones in the gallbladder, as discussed earlier in the "Biliary System" section (40,45). Similarly, use of virtual monoenergetic images can increase the conspicuity of isoattenuating cholesterol stones within the cystic duct or the common bile duct, which demonstrate higher and lower attenuation values compared with the surrounding bile at high and low keV values, respectively (40,41).…”

Section: Pancreasmentioning

confidence: 95%

“…Although energy-specific monoenergetic reconstruction algorithms have shown promise in the detection of gallstones isoattenuating to bile-with noncalcified gallstones having an attenuation lower than that of bile on images obtained with low-keV reconstruction (40 keV) and higher than that of bile on images obtained with high-keV reconstruction (≥140 keV) (39,40)-the sensitivity and specificity of these reconstruction algorithms have yet to be determined. Alternatively, material decomposition techniques with a calcium base, lipid base, or a calcium, lipid, and water base algorithm (three-material decomposition) provide excellent values for sensitivity and specificity, ranging from 80% to 95% and from 95% to 100%, respectively (41). The three-material decomposition technique is used routinely at our institution (Figs 12, 13).…”

Section: Biliary Systemmentioning

confidence: 99%

Dual-Energy CT in Evaluation of the Acute Abdomen

et al. 2019

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Evaluation of the nontraumatic acute abdomen with multidetector CT has long been accepted and validated as the reference standard in the acute setting. Dual-energy CT has emerged as a promising tool, with multiple clinical applications in abdominal imaging already demonstrated. With its ability to allow characterization of materials on the basis of their differential attenuation when imaged at two different energy levels, dual-energy CT can help identify the composition of internal body constituents. Therefore, it is possible to selectively identify iodine to assess the enhancement pattern of an organ, including the identification of hyperenhancement in cases of inflammatory processes, or ischemic changes secondary to vascular compromise. Quantification of iodine uptake with contrast material-enhanced dual-energy CT is also possible, and this quantification has been suggested to be useful in differentiating inflammatory from neoplastic conditions. Dual-energy CT can help determine the composition of gallstones and urolithiasis and can be used to accurately differentiate uric acid urinary calculi from non-uric acid urinary calculi. Moreover, dual-energy CT is capable of substantially reducing artifacts caused by metallic prostheses, to improve the imaging evaluation of abdominopelvic organs. The possibility of creating virtual nonenhanced images in the evaluation of acute aortic syndrome, gastrointestinal hemorrhage and is chemia, or pancreatic pathologic conditions substantially reduces the radiation dose delivered to the patient, by eliminating a true nonenhanced acquisition. Finally, by increasing the iodine conspicuity, contrast-enhanced dual-energy CT can render an area of free active extravasation or endoleak more visible, compared with conventional single-energy CT. This article reviews the basics of dual-energy CT and highlights its main clinical applications in evaluation of the nontraumatic acute abdomen. ©

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Clinical value of spectral CT in diagnosis of negative gallstones and common bile duct stones

Abstract: Spectral CT has a high diagnostic value for negative gallstones or bile duct stones, and material decomposition CT images and spectral curves can make an accurate diagnosis.

Cited by 21 publications

References 26 publications

Effects of low-dose energy spectrum scanning combined with adaptive statistical iterative reconstruction on the quality of imaging in Budd-Chiari syndrome

Effects of low-dose energy spectrum scanning combined with adaptive statistical iterative reconstruction on the quality of imaging in Budd-Chiari syndrome

Computed tomography imaging for the characterisation of drugs with radiation density measurements and HU spectroscopy

Dual-Energy CT in Evaluation of the Acute Abdomen

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