Clinico-epidemiological profile of cutaneous manifestations among human immunodeficiency virus positive patients in the sub-Himalayan region

Sen, Sumit; Halder, Saswati; Mandal, Sukanta; Pal, Partho Pratim; Halder, Atin; Bhaumik, Parna

doi:10.4103/0378-6323.53142

Cited by 4 publications

(8 citation statements)

References 5 publications

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“…The next manifestation in the present study was seborrheic dermatitis(8.88%). Almost similar findings were reported by other workers(8.5%) [11]. Seborrhoic dermatitis is one of the common noninfectious skin conditions in India, with a prevalence rate of 8% to 21% in HIV positive patients [8].…”

Section: Resultssupporting

confidence: 77%

“…In the present study, oral candidiasis (32.22%) was the most common mucocutaneous manifestation which was seen in the HIV positive persons, which collaborated with the findings of other workers (35.33%) [13]. It was reported to be 61% in another study which was done in the same institution [14] (p<0.001), whereas other workers had reported it to be 45% and 11.50% respectively [15,11]. Oropharyngeal candidosis has been reported to occur in from 50-95% of all the HIV positive persons at some point during their progression to full-blown AIDS [16].…”

Section: Discussionsupporting

confidence: 72%

“…In the current study, the male-female ratio was 1:1.05, which showed a slight preponderance of females over males, whereas other workers had observed a 2.2:1 male -female ratio [11]. This shows that the epidemic is increasing steadily among women and among the rural young housewives with a low level of education .In the present study, the major mode of the infection was the heterosexual route (86.6%), which almost collaborated with the data from another study (88.7%) [11].…”

Section: Discussionmentioning

confidence: 82%

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Skin and Mucocutaneous Manifestations: Useful Clinical Predictors of HIV/AIDS

Chopra

Arora²

2012

JCDR

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Background and Aims:The HIV infection is associated with several dermatological conditions which may be the first pointer towards the existence of HIV. These may present with unusual and atypical manifestations in the course of the HIV infection. Keeping this in mind, the seroprevalence of HIV in these persons and the spectrum of the skin and the mucocutaneous lesions in the HIV positive patients was studied. Methods:The current prospective study was conducted over a period of 3 years (2006)(2007)(2008). A total of 604 persons who had any kind of skin and mucocutaneous infections were screened for the HIV infection as per the NACO guidelines after recording their clinical and epidemiological profiles.

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Section: Resultssupporting

confidence: 77%

Section: Discussionsupporting

confidence: 72%

Section: Discussionmentioning

confidence: 82%

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Skin and Mucocutaneous Manifestations: Useful Clinical Predictors of HIV/AIDS

Chopra

Arora²

2012

JCDR

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“…The male:female ratio in the current study was 2:1, which is comparable to studies by Sen et al, 3 where it was 2:1, and Vijayakumari et al, 4 where it was reported to be 1.6:1. Of the 100 patients, 32 (32%), or the majority of the cases, were between the ages of 31 and 40.…”

Section: Discussionsupporting

confidence: 89%

Study of mucocutaneous manifestations in HIV-infected patients and its relation to cd4 count and stage of HIV disease

Panthalla¹,

Nookala

Kommala³

2023

IJCED

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: HIV patients frequently have mucocutaneous manifestations, which could be the first sign of the infection and can also be prognostic markers for disease progression. This study was done to note the different mucocutaneous manifestations occurring in the people living with HIV/AIDS.: One hundred ensuent HIV seropositive patients who attended the opd were included in the study.: The bulk of the study participants were illiterate, had a mean age of 32, and a male to female ratio of 2:1. The patients' number of manifestations ranged from 01 to 05. The most typical illnesses observed in this investigation were dermatophyte infections followed by oral candidiasis. The most frequent non-infectious symptoms observed in this investigation were SD and PPE. The most prevalent STI was herpes genitalis. Inversely correlated with CD4 level were the type, number, and severity of mucocutaneous symptoms. The number of manifestations and CD4 count were found to be inversely correlated. The majority of PLHAs (55%) exhibited several manifestations. The majority of the manifestations are unusual, persistent, recurrent, and resistant to the therapy. Young patients presenting with extensive SD, PPE, OC, scrofuloderma, and HZ should encourage the clinician to investigate the patient's sero-reactivity status

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“…It may occasionally present with other types of immunosuppression as well [3]. Low CD4+ counts also act as a marker of HIV disease progression [10].…”

Section: Discussionmentioning

confidence: 99%

Chronic ulcerating genital herpes simplex virus infection: A diagnosis mislead by HIV infection

Parajuli¹,

Acharya²,

Rathi³

et al. 2014

Our Dermatol Online

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We report a case of chronic herpes simplex in a 27 year old lady presenting with a history of persistent verrucous ulcer in the natal cleft of nine months duration. The patient was diagnosed and treated initially as a case of Tuberculosis Verrucosa Cutis (TVC) based on the chronicity of the ulcer, negative HIV serological tests and histopathological findings. The diagnosis had to be revised as the lesion was increasing in size and the patient was not responding to treatment even after completing antituberculous treatment for six months. Repeat histopathological examination and immunohistochemistry showed DNA of herpes simplex. Based on this finding a repeat HIV serology was sent which was positive. The ulcer healed after a course of acyclovir. The case is being reported to highlight the importance of considering chronic herpes simplex infection in a case of chronic genital ulcer. In addition this case reminds us the nature of HIV infection to mislead the diagnosis by altering the natural course of the disease process.

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Clinico-epidemiological profile of cutaneous manifestations among human immunodeficiency virus positive patients in the sub-Himalayan region

Cited by 4 publications

References 5 publications

Skin and Mucocutaneous Manifestations: Useful Clinical Predictors of HIV/AIDS

Skin and Mucocutaneous Manifestations: Useful Clinical Predictors of HIV/AIDS

Study of mucocutaneous manifestations in HIV-infected patients and its relation to cd4 count and stage of HIV disease

Chronic ulcerating genital herpes simplex virus infection: A diagnosis mislead by HIV infection

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