Clinico-Etiological Profile of Hyponatremia in Patients Admitted in Intensive Care Unit of Tertiary Health Care Rural Center

Patni, Manish; Humaney, N.R.; Jeswani, Jitesh; Deoke, S.A.

doi:10.18535/jmscr/v3i8.12

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“…in Nagpur, Maharashtra, similar findings were reported with drowsiness as the most common symptom (51%), followed by vomiting (14%) and seizures (6%). [ 13 ]…”

Section: Discussionmentioning

confidence: 99%

Clinical profile of patients admitted with hyponatremia in the medical intensive care unit

Babaliche

Madnani

Kamat

2017

Indian Journal of Critical Care Medicine

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Background and Aims:Hyponatremia is the predominant electrolyte abnormality with an incidence rate of approximately 22%. It is the leading cause of morbidity and mortality with scarce data in Indian intensive care settings. The aim of this study is to evaluate the clinical features and etiology of hyponatremia in patients admitted to an Intensive Care Unit (ICU) of a tertiary care hospital.Materials and Methods:A 1-year prospective cross-sectional observational study was conducted, including 100 adult patients with moderate-to-severe hyponatremia admitted to the Medical ICU. Patients underwent investigations such as serum creatinine, blood urea nitrogen, serum osmolality, serum sodium, urine sodium, and urine osmolality, sputum culture, cerebrospinal fluid analysis, and neuroimaging. Data were analyzed using independent sample t-test, Chi-square test, and Fisher's exact test.Results:Vomiting (28) followed by confusion (26) was the most common complaint. Syndrome of inappropriate antidiuretic hormone secretion (SIADH) (46) was the most common etiology for hyponatremia, and euvolemic hypoosmolar hyponatremia (50) was the most common type of hyponatremia. Confusion was significantly high in patients with severe hyponatremia as compared to patients with moderate hyponatremia (22 vs. 4, P < 0.001). In majority of the patients (46), SIADH was the main cause of euvolemic type of hyponatremia (P < 0.001). Increased urine sodium levels were observed in patients with SIADH (46), renal dysfunction (12), and drug-induced etiology (8, P < 0.001).Conclusion:Patients with hyponatremia secondary to an infectious cause should be meticulously screened for tuberculosis. The timely and effective treatment of hyponatremia is determined by the effective understanding of pathophysiology and associated risk factors of hyponatremia.

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“…in Nagpur, Maharashtra, similar findings were reported with drowsiness as the most common symptom (51%), followed by vomiting (14%) and seizures (6%). [ 13 ]…”

Section: Discussionmentioning

confidence: 99%

Clinical profile of patients admitted with hyponatremia in the medical intensive care unit

Babaliche

Madnani

Kamat

2017

Indian Journal of Critical Care Medicine

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Clinicaland Etiological Profile of Patients Presenting With Hyponatremia

Mehta¹,

Akash²,

Jana

2020

ijsr

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Introduction: Hyponatremia is a common electrolyteabnormality in hospitalized patients. It is defined as serum sodium concentration less than 135mEq/L. It occurs due to disruption of sodium and water homeostasis. Clinical presentation varies from asymptomatic patients to ones having seizures and coma. Aims and objective: To delineate the clinical profile and causes of hyponatremia in patients admitted in a medical ward. Material and methods: This study was conducted on 100 patientsadmitted in medicine ward of Darbhanga Medical College and Hospital,Laheriasarai, Bihar, India from October 2018 to September 2019. Patients older than 18 years with serum sodium less than 135mEq/L were included in the study. Detailed history, clinical examination and all necessary investigations were done accordingly. P value <0.05 was taken as statistically significant. Results: In the present study 72% patients were male, and 84% ofpatients was older than 50 years. Symptomatic hyponatremia in mild, moderate and severe groups were present in 42.8%, 84.8%, 96% respectively. Out of 100 cases of hyponatremiaeuvolemic, hypervolemic and hypovolemic cases were 47%, 33% and 20% respectively. Most common cause was gastrointestinal loss (24%) and most common symptom(24%) was altered sensorium in. Interestingly 10% cases of hyponatremia had history of salt restriction. Conclusion: Hyponatremia is a commonly encountered electrolyteimbalance in hospitalized patients mostly in temperate countries like India. Most common cause being gastrointestinal loss followed by diuretic use. Restricted salt intake advised by physicians or family members is also an important factor of it.

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Clinico-Etiological Profile of Hyponatremia in Patients Admitted in Intensive Care Unit of Tertiary Health Care Rural Center

Cited by 2 publications

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Clinical profile of patients admitted with hyponatremia in the medical intensive care unit

Clinical profile of patients admitted with hyponatremia in the medical intensive care unit

Clinicaland Etiological Profile of Patients Presenting With Hyponatremia

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