Clinico-Haematological Profile of patients with Mixed Phenotype Acute Leukemia: In a Tertiary Care Centre

Abstract

Introduction: Mixed phenotype acute leukemia (MPAL) is a rare subset of acute leukemia where the blasts exhibit lineage specific antigens of more than one lineage. Flow cytometric immunephenotyping is essential for the diagnosis of MPAL and the accurate diagnosis highly depends on the panel of markers used. The aim of the study is to study the incidence, clinical presentation, haematological parameters, immunophenotypic, molecular features of MPAL and their correlation to the treatment and prognostic significance. Materials and Methods: Cases of Acute Leukemia consisting of both the paediatric and adult age group admitted to the