Clinico-histopathological correlation of leprosy in western region of Nepal-A pioneer pilot study

Pokhrel, Kumar; Parajuli, Sudip; Shah, Mahesh; Subedi, Sushma

doi:10.5958/2455-6769.2016.00005.3

Cited by 8 publications

(5 citation statements)

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“…According to this study, patients below 7 years were affected the least. Similar observations were made by Guha et al, 10 Kaur et al, 11 Sehgal et al, 12 Moorthy et al, 13 Kaur et al, 14 Thakkar et al, 15 Swarnakumari et al, 16 Premalatha et al, 17 Pokhrel et al 18 Thus, the age distribution observed in present study correlates well with that of the other previous studies. The frequency of leprosy cases in children is an indicator of the level of transmission of the disease in the community.…”

Section: Discussionsupporting

confidence: 92%

A clinico-bacteriological study of leprosy cases in a tertiary care hospital of North-East India

Ak¹,

Simi²,

Kataki³

et al. 2019

International Journal of Health Research and Medico Legal Practice

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Introduction: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Although the elimination target has been achieved at the national level, leprosy still continues to be an important disease in several parts of India. Slit-skin smear microscopy plays an important role in an early and accurate diagnosis. Materials and methods: All clinically suspected referred cases of leprosy from dermatology department during the time period were included in the study. After taking detailed history and physical examination, Slit Skin Smears were done in all cases. All the slit skin smear were examined by doing Z-N staining and cases were classified as multibacillary or paucibacillary on the basis of result of smear examination. Result: Out of 144 cases, 72.22% (104/ 144) were male and 27.78% (40/144) were female. Age of the patients ranged from 7 years to 72 years. Majority of cases 48.61% (70/144) were of age group 20-39. Majority of the patients (121/144, 84.03%) were from lower socioeconomic background where as 15.97% (23/144) patients were from middle income group. Hypopigmented patch (63.89%, 92/144) and nodular lesions (59.72%, 86/144) were common presentations and few cases with loss of extremities along with ulcer. Out of 144 cases, 36 cases (25%) showed smear positive and 108 cases (75%) showed smear negative on slit skin smear examination. Conclusion: So many years after the study, leprosy still remain as important problem to bring it under expected level of control. This study indicates high circulation of lepra bacilli in the community in the "elimination era". There is an urgent need for early diagnosis and appropriate treatment to prevent spread of the bacilli and development of disabilities.

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Section: Discussionsupporting

confidence: 92%

A clinico-bacteriological study of leprosy cases in a tertiary care hospital of North-East India

Ak¹,

Simi²,

Kataki³

et al. 2019

International Journal of Health Research and Medico Legal Practice

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“…In another study conducted in Nepal among school-going adolescents, girls have reported concerns regarding the loss of virginity, leakage, and loss of fertility. Moreover, in this study, it was also reported that support from the teachers, family members, and also from peers can help significantly reduce the stigma associated with the use of the menstrual cup [13] . However, in the present study, the acceptability of the menstrual cup among the study participants was low.…”

Section: Discussionmentioning

confidence: 62%

Knowledge, attitude, and practices regarding menstrual cup among reproductive women in a rural tertiary care Hospital

Meghana¹,

Gomathy²

2021

Int. J. Clin. Obstet. Gynaecol.

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Background:The menstrual cup is a recently developed alternative to sanitary napkins. Hence, in this present study, the knowledge, practices, and attitudes of menstrual cups among rural adult women were evaluated. Methods: This cross-sectional study was conducted on women who are in the age group of 18-45 years and are willing to participate in the study. The relevant data were collected using a preformed questionnaire. The questionnaire included all the data about the demographic parameters including age, educational level, and profession, participant's knowledge about the menstrual cup, concerns, and attitude towards the same. After the data was obtained they were entered in excel and descriptive analysis was done by calculating the percentage. The appropriate diagrams were also done for data interpretation. Results: In this study total of 120 participants were included. Among them, 80% of the study participants were aware of the menstrual cup. 36.7% of the participants got information from media, 26.7% from family, 20.8% from friends, and 14.2% from media personnel. The maximum of participants was in the age group of 21 years to 30 years (58.33%). The educational level of the participants was mostly in the undergraduate (35%) or post-graduate level (25.8%). The main concern about the menstrual cup was found to be fear of leakage (51.7%), followed by discomfort (26.7%). 65% of the participants said if a menstrual cup is made available they are willing to use it. Conclusion:This study thus concluded that though many of the participants were aware of the usage of the menstrual cup the acceptance of the cup is still not achieved.

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“…In our study, histopathology revealed that the TT type of leprosy was the most often found type in 9 cases (36%), followed by the BT type in 6 cases (24%), the BL type in 4 cases (16%), the BB and LL types in 2 instances, and the histoid and undetermined types in [17,[19][20][21]. These variation can be due to regional differences, socioeconomic and immune status of population studied.…”

Section: Discussionmentioning

confidence: 69%

A Retrospective Study of Histomorphological Spectrum of Hansen’s Disease in a Tertiary Care Centre of Barabanki Area

Radha

Goyal

Choudhary

et al. 2023

Asian J Pharm Clin Res

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Objectives: Hansen’s disease is a chronic granulomatous infectious disease caused by Mycobacterium leprae. Early detection is essential to prevent the disease’s spread and disability. Due to the multitude of morphologies, it may be difficult to accurately diagnose certain cases based solely on clinical signs; therefore, histopathology is crucial for definitive diagnosis. The study aims to investigate the various histological forms of leprosy over a year in a tertiary care hospital. Methods: It was a retrospective study that included 25 leprosy cases that were clinically and histopathologically diagnosed from July 2021 to August 2022 in a tertiary care center. Results: The majority of the cases were from the second decade with the male predominance of the cases (M:F=1.5:1). According to histomorphology, tuberculoid leprosy was the most common type (36%), followed by borderline tuberculoid (24%), borderline lepromatous (16%), lepromatous leprosy (8%), borderline leprosy (8%), histoid leprosy (4%), and indeterminate leprosy (4%). Ziehl–Neelsen staining for acid-fast bacilli demonstrated positivity in 8 cases. Conclusion: As the clinical spectrum of leprosy is diverse, histopathology is the gold standard for the diagnosis and a key tool in obtaining a conclusive diagnosis.

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Clinico-histopathological correlation of leprosy in western region of Nepal-A pioneer pilot study

Cited by 8 publications

References 0 publications

A clinico-bacteriological study of leprosy cases in a tertiary care hospital of North-East India

A clinico-bacteriological study of leprosy cases in a tertiary care hospital of North-East India

Knowledge, attitude, and practices regarding menstrual cup among reproductive women in a rural tertiary care Hospital

A Retrospective Study of Histomorphological Spectrum of Hansen’s Disease in a Tertiary Care Centre of Barabanki Area

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