Clinico-pathological features of bladder carcinoma: Experience from a tertiary care hospital of Pakistan

Rafique, Muhammad; Javed, Abrar Ahmed

doi:10.1007/s11255-006-6676-1

Cited by 14 publications

(15 citation statements)

References 16 publications

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“…Urothelial tumors were the only histological type seen in our study which was also reported (Rafique et al, 2006;Al-Bazzaz, 2009). Bladder cancer is rare in people younger than 50 years of age even though it can occur at any age.…”

Section: Discussionsupporting

confidence: 86%

Urothelial Tumors of the Urinary Bladder in Manipur: A Histopathological Perspective

Laishram¹,

Kipgen²,

Laishram³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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The study included 26 cases of transitional cell tumors of urinary bladder. The male to female ratio was 1.5: 1 and the ages ranged from 38 years to 73 years (medians of 60 and 64 years, respectively). Of the total, 14 (53.9%) cases were low grade, 9 (34.6%) were high grade, 2 (7.7%) were papillomas and 1 (3.9%) was a papillary urothelial neoplasm of low malignant potential (PUNLMP). Pathological staging showed that 14 (53.9%) of the cases were stage PTa, four (15.4%) PT1, and eight (30.9%) PT2. Some 18.2% of low grade tumors and 75% of high grade tumors were invasive to the detrusor muscle layer. Conclusion: Bladder cancer is an uncommon disease, transitional tumors being the only histological type observed. It was more common in males than females, with peak incidence in seventh decade. Most of the tumors were non-invasive (PTa) and invasion to the detrusor muscle layer was seen in more than half of the high grade tumors. There is a definite correlation between advancing tumor grade and muscle invasion.

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Section: Discussionsupporting

confidence: 86%

Urothelial Tumors of the Urinary Bladder in Manipur: A Histopathological Perspective

Laishram¹,

Kipgen²,

Laishram³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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“…As many as 50% cases of bladder cancer are attributed to smoking in men and 33% in women. 1 In our study out of 30 patients 23 (75.9%) patients were smokers. The incidence in our study of male smoker is 75.9%, which is comparable to that of 65% of bladder cancer in men is attributed to cigarette smoking.…”

mentioning

confidence: 51%

“…1 So we reached at a conclusion that factory workers (Textiles, tyre rubber and cable worker) are at high risk for CA urinary bladder in our country. A lot of other carcinogens or highrisk occupations are still to be detected apart from those present in the literature.…”

Section: Discussionmentioning

confidence: 83%

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Carcinoma of Urinary Bladder; Extent of Carcinoma of Urinary Bladder on First Presentation and Its Impact on Management

Hussain

Khan

et al. 2017

TPMJ

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“…The average age at diagnosis of bladder cancer patients in Sri Lanka is similar to that of India which is around 65 [ 15 ]. In Pakistan the mean age of bladder cancer is around 55–58 years [ 17 , 18 ]. In the present study male to female ratio was 4.1 : 1, compared to the ratio of 3 : 1 quoted worldwide [ 3 , 21 ].…”

Section: Discussionmentioning

confidence: 99%

Pathological Characteristics of Primary Bladder Carcinoma Treated at a Tertiary Care Hospital and Changing Demographics of Bladder Cancer in Sri Lanka

Sasikumar

Wijayarathna

Karunaratne

et al. 2016

Advances in Urology

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Objectives. The aim was to compare demographics and pathological features of bladder carcinoma treated in a urology unit with findings of previous studies done in Sri Lanka. Materials and Methods. Data of newly diagnosed patients with bladder cancer in a tertiary referral centre from 2011 to 2014 were analysed. Data on bladder cancers diagnosed from 1993 to 2014 were obtained from previous publications and Sri Lanka Cancer Registry. Results. There were 148 patients and mean age was 65 years. Male to female ratio was 4.1 : 1. Urothelial carcinoma (UC) was found in 89.2% of patients. Muscle invasion was noted in 35% of patients compared to 48.4% two decades ago. In patients with UC, 16.5% were found to have pT1 high grade tumour. It was 5.3% from 1993 to 2000. Pure squamous cell carcinoma was found in 8.1% of patients while primary or de novo carcinoma in situ (not associated with high grade pT1 tumours) was seen in one patient only. Conclusions. The percentage of squamous carcinoma is higher among Sri Lankan patients while primary carcinoma in situ is a rarity. The percentage of muscle invasive disease has decreased while the percentage of pT1 high grade tumours has increased during the last two decades in Sri Lanka.

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Clinico-pathological features of bladder carcinoma: Experience from a tertiary care hospital of Pakistan

Abstract: More than 90% of primary bladder carcinoma are of transitional cell variety and over 60% having muscle invasive disease at the time of diagnosis. Even in patients with superficial disease, majority (i.e. 98%) have invasion of lamina propria.

Cited by 14 publications

References 16 publications

Urothelial Tumors of the Urinary Bladder in Manipur: A Histopathological Perspective

Urothelial Tumors of the Urinary Bladder in Manipur: A Histopathological Perspective

Carcinoma of Urinary Bladder; Extent of Carcinoma of Urinary Bladder on First Presentation and Its Impact on Management

Pathological Characteristics of Primary Bladder Carcinoma Treated at a Tertiary Care Hospital and Changing Demographics of Bladder Cancer in Sri Lanka

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