Clinico-pathological profile of bronchogenic carcinoma cases presented to Chest Department, Cairo University in the last 10 years

Clinical and Pathological Presentations of Bronchogenic Carcinoma in a Tertiary Care Centre

“…In a study conducted by Yosri M. Aklet al, 14 four types of bronchogenic carcinoma were found; squamous cell carcinoma 37.4%, adenocarcinoma 29.5%, small cell carcinoma 14.9%, large cell carcinoma 7.2% and undifferentiated carcinoma 11.1%; whereas in a study done by Sundaram et al, 12 they found squamous cell carcinoma, adenocarcinoma, small cell carcinoma and large cell carcinoma were seen in 31.67%, 43.33%, 10% and 3.24% cases, respectively; 11.67% patients showed malignant cells only and marked as unclassified.…”

Characteristics, risk factors and histopathological types of bronchogenic carcinoma among cases presented to Chest Department, Al-Zahraa Hospital, Al-Azhar University

“…Alongside; another study reported that most cases of bronchogenic carcinoma were in their sixth and seventh decade at time of diagnosis; where cases with SCC tend to be older than those with either SCLC or ADC. 5 While, Gupta et al demonstrated that the highest prevalence of bronchogenic carcinoma was seen between 50-59 years of age. …”

“…Similarly, other studies reported male predominance among bronchogenic carcinoma cases. 5,18,2,19 The higher incidence of lung cancer in men probably mirrors the higher rate of smoking among men while, it is less prevalent among women in Arab nations. Other factors, such as sex-linked genetic susceptibility or sex hormones, may be responsible for some of the genderrelated differences in lung cancer risk.…”

“…20 Furthermore, other studies reported higher percentages of smokers among cases of lung cancer. 5,19 The occurrence of lung cancer in non-smokers could points to the possible existence of carcinogenic factors other than smoking. Also, Sen et al stated that ADC was significantly higher in non-smokers than smokers.…”

“…5 There are various important risk factors other than tobacco smoking that can contribute substantially to the lung cancer mortality in never smokers; these other lung carcinogens often act in an additive or synergistic manner in individuals who smoke tobacco products. 6 Globally, 19% of all cancers are attributable to the environment and the rising air pollution, including work setting, some industrial materials, particularly asbestos.…”