Clinicopathologic correlation of lymphography and lymph node metastases in gynecological neoplasms

Benninghoff, David L.; Herman, Peter C.; Nelson, James H.

doi:10.1002/1097-0142(196606)19:6<885::aid-cncr2820190622>3.0.co;2-s

Cited by 8 publications

References 6 publications

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Prospects for para-aortic irradiation in treatment of cancer of the cervix

Chism

Park

Keys

1975

Cancer

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The incidence of para-aortic node metastasis in cancer of the cervix ranges from 5%to 50% in clinical Stages i-iv. Extended field irradiation is being administered more frequently because of high incidence of extrapelvic disease. The cancer of the cervix material at Walter Reed General Hospital has been analyzed as to site and time of failure to determine who might have benefited from extended field irradiation. Of patients who fail, the majority will have uncontrolled pelvic disease regardless of other involvement. Diagnostic procedures including staging laparotomy are unable to predict pelvic failure or the presence of occult distant disease in lung and bone. The maximum number of patients who could benefit from pari-aortic irradiation is lessthan 3% of a total series. It is concluded that the salvage of patients with para-aortic metastasis will be small, but for those few long-term survivors, the benefit will be great.

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Prospects for para-aortic irradiation in treatment of cancer of the cervix

Chism

Park

Keys

1975

Cancer

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Intralymphatic bcg in the treatment of gynecologic malignancies.A phase I study

Mangan

Jeglum

Sedlacek

et al. 1977

Cancer

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Thirteen patients with a variety of advanced gynecologic malignancies were administered BCG via the dorsal lymphatics of the lower extremity in addition to standard accepted forms of therapy. Prolonged febrile courses, lymphangitis and suppurative adenitis were observed along the lymphatic pathway of the injected lower limbs. There was no correlation between reaction to a standard anergy panel and survival. There was also no correlation between reaction to a standard anergy panel and the inflammatory response to intralymphatic BCG (ILP-BCG). There was, however, a positive correlation between the inflammatory response to ILP-BCG and survival. Intralymphatic administration of immunostimulants may conceivably be of value as ancillary therapy for use in gynecologic malignancy. However, complications of this approach to immunotherapy are significant and the method should not be used until complications are decreased.

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Diagnosis of Cancer Metastases in Lymph Nodes

Fuchs¹

1969

Recent Results in Cancer Research

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Clinicopathologic correlation of lymphography and lymph node metastases in gynecological neoplasms

Abstract: A correlation of lymphography with histology was determined in 28 patients with gynecological tumors. Lymphography was of limited value in detecting early metastases but was a reliable indicator when extensive lymphatic involvement was present.

Cited by 8 publications

References 6 publications

Prospects for para-aortic irradiation in treatment of cancer of the cervix

Prospects for para-aortic irradiation in treatment of cancer of the cervix

Intralymphatic bcg in the treatment of gynecologic malignancies.A phase I study

Diagnosis of Cancer Metastases in Lymph Nodes

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