Clinicopathological Analysis of Hysterectomy Specimens

Abstract

Introduction:The uterus is vital reproductive organ prone to develop several non-neoplastic and neoplastic lesions in woman contributing significantly to increased morbidity and mortality. Although many treatment options are available, hysterectomy isstill widely used treatment modality worldwide. Objectives: The study was proposed to analyse the patterns of lesions in hysterectomy specimens and to analyse the clinico-pathological correlation in hysterectomy specimen. Methods: A 6-month retrospective study was performed in Department of Pathology, Karwar institute of Medical science, Karwar. Baseline data were collected from inpatient files and histopathology reports were collected from Department of Pathology, to identify the most common pathologies in hysterectomy specimens. Results: 78 hysterectomy cases were analysed and the peak age group were from 35-45 years (42.30%), and the most common clinical presentation was fibroids (42.30%). Most common histopathological lesion was leiomyoma 37 cases (47.4%), followed by 16 cases (12.82%) presented as adenomyosis, and 14 cases (10.26%) had dual pathology of both leiomyoma and adenomyosis. The commonest incidental histopathological finding seen in hysterectomy specimens was chronic cervicitis. Conclusions: Hysterectomy is the most commonly performed elective major gynaecological surgery. Though the histopathological analysis correlates well with the clinical diagnoses, quite a few lesions like chronic cervicitis and adenomyosis were encountered as pure incidental findings. Hence, it is mandatory that every hysterectomy specimen, even if it grossly appears to be normal, should be subjected to detailed histopathological examination for confirming diagnosis and better postoperative management.

Histopathological analysis of gynaecological hysterectomy specimens at a tertiary care hospital in southern Nigeria

“…In our study, the majority of the 202 hysterectomies were performed between the ages of 35 and 44, with the fewest occurring between the ages of 55 and 64. These findings are consistent with previous research conducted [12][13][14] . The abdominal route was the most used method of hysterectomy.…”

“…The most common reason for hysterectomy in our study was uterine fibroids, which is consistent with previous reports in the literature [3,13,19,20,21] . Histopathological examination of…”

“…Only three cases had cystic glandular hyperplasia, which is consistent with the diagnosis of DUB, while the remaining women who underwent hysterectomy for this diagnosis had adenomyosis, endometrial polyp, secretory endometrium, or disordered proliferative endometrium. Other authors made similar observations [13,30] . Chronic cervicitis was identified as the most common pathological finding in the cervix.…”

“…The most common myometrial finding was Leiomyoma. Other researchers reported similar findings [11,13,17,18,20,27,[29][30][31] . Adenomyosis, defined as the presence of endometrial glands and stroma deep within the myometrium, is the second most common myometrial pathology in this study.…”

“…Similar findings to the current study were obtained by Usha et al [23] Rather et al [3] and Imam et al [24] In addition, Verma et al [4] identified proliferative endometrium as the most common finding. Other researchers also made similar observations [13,17,20,25] . This concordance may be due to the women in these studies being of similar ages.…”