Clinicopathological Characteristics of Ocular Surface Squamous Neoplasia: A 10-Year Review form a Referral Tertiary Centre in Nigeria

Abstract

Background: Ocular surface squamous neoplasia is a heterogenous group of proliferative squamous lesions on the ocular surface with varying biologic behaviours. This study aims to report the clinical profile and pathologic characteristics of cases of OSSN seen at a tertiary referral centre in North West NigeriaMethods: A retrospective review of all cases of OSSN diagnosed over a 10-year period was doneResults: OSSN accounted for 68 out of 91 ocular surface lesions affecting twice as many males as females and a peak incidence in the 30-39 years age group. They frequently presented as higher grade and higher stage lesions with invasive squamous cell carcinoma being the most frequently diagnosed OSSN. They also frequently show association with HIV infection and a relatively long duration of symptoms before presentationConclusion: OSSN occur in a relatively young age group in our environment. Certain clinical and epidemiological features appear to [predict the occurrence of higher grade lesions and this may help in the clinical prediction of likely pathologic grade and/or biologic behaviour of these lesions.

Demographics, clinical presentation and risk factors of ocular surface squamous neoplasia at a tertiary hospital, South Africa

“…This differs from other African countries where SCC was the dominant histological nding. 15,17,29 Our study resembles the histological pro le of developed nations. 17,18,21,24,30 Our study was conducted in an urban environment where there is easy access to healthcare services.…”