Clinicopathological correlation in the diagnosis of skin diseases: A retrospective study

Shankar, Prerna; Venugopal, Ruby; Pathania, Vikas

doi:10.4103/mjdrdypu.mjdrdypu_5_20

Cited by 4 publications

(7 citation statements)

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“…Histiocytic lesions (dermatofibromas, dermatofibrosarcoma protuberans, xanthomas, xanthelasma) are close differentials clinically and serve as differential diagnosis for one another leading to a poor definitive diagnosis of these disorders. In consonance with this study, Venugopal had a better correlation with benign lesions (10). George et al and Al-Saif et al in their studies were however at variance with this study as they reported a better CPC with malignant lesions (4,12).…”

Section: Discussionsupporting

confidence: 81%

“…The level of CPC in this study is within the range of what is documented in similar histopathology studies (4,9,11,19,20). The CPC tends towards a high level when most of the clinical diagnosis is made by dermatologists because they are trained to recognise these lesions clinically (8,10,12,19). The level of CPC in this study was dependent on the diagnosis with alopecia and scalp disorders having the highest CPC followed by infectious diseases and inflammatory diseases.…”

Section: Discussionmentioning

confidence: 78%

“…In some studies, neoplastic diseases have a higher CPC (12) while in others, it is inflammatory diseases (4) and in others there is . no difference (10) Amongst the neoplastic diseases CPC was best with the benign lesions: lipomas followed by mesenchymal and then epidermal lesions. CPC was lowest with histiocytic lesions.…”

Section: Discussionmentioning

confidence: 92%

“…The studies on the histopathologic correlation of clinical diagnosis made of skin disease show a correlation of 23.3% to 94.9% (4,(6)(7)(8)(9). These studies also reveal a correlation between the histopathologic and the first clinical diagnosis in 47.4 to 82.3% and a correlation with the clinical differential diagnosis in 7.4 to 13.9% (10,11). Furthermore, a higher correlation is reported when the clinical diagnosis is made by dermatologists.…”

Section: Introductionmentioning

confidence: 77%

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A cliniccopathologic correlation study of 2396 histopathologic skin biopsy specimens

Anaba¹,

Dawodu²,

Arabambi³

2023

REJHS

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Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 92%

Section: Introductionmentioning

confidence: 77%

See 2 more Smart Citations

A cliniccopathologic correlation study of 2396 histopathologic skin biopsy specimens

Anaba¹,

Dawodu²,

Arabambi³

2023

REJHS

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“…The neoplastic lesions especially the malignant cases were found mostly in head and neck region. The non infectious benign disorders were seen on trunk followed by the extremities 30 pathological harmony was found to be 67.5% 31 . The clinicopathological harmony was eminent for malignant cases (97 %).…”

Section: Discussionmentioning

confidence: 91%

Histopathological Review of Skin Diseases: A Three Years Survey of 510 Skin Biopsies in Multan

Ali¹,

Ali²,

Kanwar³

et al. 2023

PJMHS

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Introduction: Skin ailments share a major disease burden worldwide (1, 2).They are considerably frequent in underdeveloped nations and encompass simple ailments like inflammation and pimples to certain grave diseases like skin melanomas (3). However, the type and prevalence of skin disorders differ from area to area on account of dissimilar habitat (4, 5). Skin disorders influence human lives in various ways and many a times the dermal epidermal conditions point some internal ongoing serious disease (6). A vast majority of skin diseases are treated on the basis of clinical diagnosis without confirmation through biopsy. Microscopic examination is mandatory for verification and precise diagnosis and to direct the clinician to opt suitable treatment (7). Considering their importance, the research work being done on the prevalence of specific disorders in particular regions in our country appears deficient especially considering the clinicopathological consonance. The current research was outlined to acumen the skin diseases related burden in our institute. Aim & Objective: The aim of this research is to evaluate the histopathological diversity of skin diseases and their prevalence in Multan region along with the clinic-pathological consonance. Study Design: Retrospective cross sectional study Place and Duration: Histopathology and dermatology departments of Bakhtawar Amin Medical & Dental College and Trust Hospital Multan, from January 2020 to December 2022. Material and Methods: Histopathological reports of all skin biopsies were sorted. The required data like age, gender, clinical presentation, site of the lesion, dermatologist’s findings, and their clinical provisional impression with differential diagnoses were documented along with the histopathological microscopic opinion. The particulars were gathered from clinical files, histopathological demand forms and documented reports. Results: A sum of 510 skin biopsies was received in histopathology section. Out of these, 280 (54.9%) were females and remaining 230 (45.1%) were males. The mean age was 34.70 years (ranging from 2 to 84 years). Most of them were between ages 16-30 years. Majority of the lesions were benign non cancerous and related to skin appendages. Epidermal inclusion cyst appeared to be the most prevalent. Out of 510 biopsies, 68 (13.3%) turned out to be malignant neoplasms. Conclusion: A vast majority of skin diseases are treated only on the basis of clinical diagnosis. The present study revealed that the histopathological opinion was consistent with the clinical judgment in 63 % of the cases, unveiling the significance of histopathological examination that is must for saving time and expenses of the patients. It also helps in reduction of the morbidity related to various skin disorders Keywords: Histopathology, dermatology, skin disorders, skin cancers, epidermal inclusion cyst

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Skin lesions in children: evaluation of clinicopathological findings

Calim-Gurbuz¹,

Pehlivanoğlu²,

Soylemez-Akkurt³

et al. 2023

TJPATH

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Objective: Pediatric skin diseases may show various manifestations, occasionally affecting the patients' quality of life. Histopathological examination may be required for the diagnosis. The aim of this study was to evaluate the spectrum of clinicopathological features in pediatric skin lesions. Material and Method:A total of 368 biopsies of 359 consecutive patients were included. The clinicopathological findings were retrospectively evaluated. Non-neoplastic (inflammatory) lesions (ILs) (n=186) were grouped per their origin, while neoplastic/proliferative lesions (NPLs) (n=182) were grouped based on their pattern. The clinical and histopathological characteristics were statistically analyzed.Results: 51% were male and the median age was 10.4±4.9 years (range 0-17). ILs mainly involved the head and neck, and NPLs were mostly located in the lower extremity (p<0.001). The most common NPLs were benign nevus (18%, n=33) and pilomatrixoma (15%, n=27), while the most frequent IL was spongiotic/psoriasiform dermatitis (38%). Skin appendage/connective tissue tumors were the largest among NPLs (p=0.02). NPLs were more frequently seen in children >12 years old compared to ILs (p=0.03). The discordance rate between clinical and histopathological diagnoses was higher for NPLs (27% vs. 15%). Conclusion:Although the spectrum of skin lesions is broad in pediatric patients, most are benign in nature. The higher frequency of melanocytic and/or cystic lesions among children >12 years old may be attributed to increased self-care during puberty. Neoplastic/proliferative lesions of childhood seem to be less commonly recognized by clinicians, and a multidisciplinary approach remains the optimal method, considering the relatively high rate of discordance between the clinical and histopathological diagnoses.

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Clinicopathological correlation in the diagnosis of skin diseases: A retrospective study

Cited by 4 publications

References 0 publications

A cliniccopathologic correlation study of 2396 histopathologic skin biopsy specimens

A cliniccopathologic correlation study of 2396 histopathologic skin biopsy specimens

Histopathological Review of Skin Diseases: A Three Years Survey of 510 Skin Biopsies in Multan

Skin lesions in children: evaluation of clinicopathological findings

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