Clinicopathological spectrum of uterine leiomyomas in a state of Northern India: a hospital based study

Clinicopathological study of leiomyomas in hysterectomy specimens

“…In a study conducted by Geethamala et al, 93.8% cases were seen in multiparous women and 1.6% in nulliparous. 7 Similar results were seen in a study conducted by Begum and Khan, Chethana et al and Lahori et al [9][10][11] In this study, the most common histopathological diagnosis in endometrium was proliferative phase (46.15%) followed by endometrial hyperplasia (19.23%). This was comparable with the study conducted by Geethamala et al, in which proliferative phase was seen in 50.7% and simple hyperplasia in 22.7%.…”

“…The results were comparable to the study conducted by Lahori et al in which secondary changes were seen in 16.46% cases. 11 Among these, 6.33% showed hyaline change which constituted the most common secondary change, 3.8% showed myxoid change, 3.8% showed calcification, 3.8% showed cystic and 2.53% demonstrated red (carneous) degeneration. Jung et al found secondary changes in 9.2% cases and the most common change was hyaline degeneration (5.7%).…”

“…Intramural was the most common site of leiomyoma in a study by Kulkarni et al (60%) and Lahori et al (57.43%) and Gowri et al (48%). 12,11,5 Most of the cases with subserosal fibroid presented with pain abdomen, while most of the cases with submucosal fibroid presented with irregular bleeding. Subserosal fibroids can cause pain due to compression or torsion (if they are pedunculated).…”

Leiomyomas in Hysterectomy Specimens: A Clinicohistopathological Study

“…Leiomyomas are mostly asymptomatic but when symptomatic, most common clinical manifestation is menorrhagia due to increased vascularity, endometrial surface and altered uterine contractility which was chief complaint in 45.97% cases in our study and studies of Geethamala et al 12 49.36%, Kaur et al 13 51.54%, Abraham and Saldanha 10 40%. It is followed by pain abdomen possibly due to degenerative changes in leiomyomas, seen in 19.23% cases in our study, similar to Lahori et al 11 In our study leiomyomas in uterus were singly seen in 52.01% uteri and multiple fibroids were seen in 48.99% uteri. Similar occurrence was also seen by Lahori et al 11 (56.96%), while Geethamala et al 12 had a higher incidence (70.9%) of unitary fibroids.…”

“…Number 10 Lahori et al, 11 Geethamala et al 12 and Kaur et al 13 The specimen obtained was most commonly uterocervix with bilateral adnexa (66.23%), while only uterocervix was obtained in 22.45% cases and uterocervix with one sided adnexa was excised in 11.32% cases. Comparable data was seen in study of Geethamala et al 12 with abdominal hysterectomies in 80.24% and vaginal hysterectomies in 19.76%.…”