1970
DOI: 10.1016/s0140-6736(70)91268-7
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Clinicopathological Study of Nephrotic Syndrome in Childhood

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Cited by 280 publications
(171 citation statements)
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References 30 publications
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“…While more boys have MCNS, the other variants are more common in girls. 10 Children 6 years and under are more likely to have MCNS than other lesions (87% versus 13%). 4 The most common variant among African-American children is FSGS, accounting for 47% of cases with nephrotic syndrome.…”
Section: Epidemiologymentioning
confidence: 99%
See 2 more Smart Citations
“…While more boys have MCNS, the other variants are more common in girls. 10 Children 6 years and under are more likely to have MCNS than other lesions (87% versus 13%). 4 The most common variant among African-American children is FSGS, accounting for 47% of cases with nephrotic syndrome.…”
Section: Epidemiologymentioning
confidence: 99%
“…Most patients with MCNS respond to corticosteroid therapy, with only 2-7% 4,5,10 being steroid resistant. In contrast, most (83%) patients with FSGS are steroid resistant, 5 and studies have reported that 72-90% 4,5,10 of all non-MCNS variants are steroid resistant, ranging from 100% of those with membranous nephropathy to 25% of those with focal global glomerular obsolescence with tubular atrophy. 4 In its early stages, FSGS may be difficult or impossible to distinguish from MCNS, depending on issues of sampling and extent of involvement.…”
Section: Description Of Health Problemmentioning
confidence: 99%
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“…Of the 28 nephrotic syndrome (NS) child patients on whom biopsy was canied out, 20/28 (or 71.4%) were inales and 8/28 (or 28,6%) were females, giving a male to female, ratio of 2.4; 1. This ratio did not differ substantially from the range of 2,0 : 1 to 2,6 : 1 reported by Habib 4 and White et al 2 The report of Chaw et al 5 also showed the domination of male patients in NS children. The implementation of routine kidney biopsy on all NS patients has been disconti.nued, 6 ' 7 due to the fact that primary NS data collection had shown that a larger proportion belong tQ the minimal changes nephrotic syndrome (MCNS).…”
Section: P Daman/k Eta/ 25mentioning
confidence: 42%
“…In this study, FSGS was detected in 10%, DMP in 3% and other forms of glomerulonephritis were detected in 10% of renal biopsy specimens. 2 Like these observations MCNS formed 88% of biopsies in the study of White et al 18 Ejaz et al performed renal biopsies in children who had SDNS, SRNS and FRNS and they found out that FSGS formed 42% and MCNS 22% of renal biopsy specimens. 19 We also performed renal biopsies in 73 children who were either SDNS, SRNS or FRNS.…”
mentioning
confidence: 83%