Clinicopathological study of Sinonasal Masses

Mane, Prashant Shivaji; Agale, Shubhangi Vinayak

doi:10.21276/apalm.1207

Cited by 12 publications

(26 citation statements)

References 10 publications

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“…Similar findings of male preponderance were observed in studies conducted by Tondon et al, 10 Khan et al 11 and Kulkarni et al 6 We observed higher frequency of non-neoplastic lesions (80.33%) in comparison with neoplastic lesions (19.67%). Our findings are in concordance with Khan et al, 11 Kulkarni et al 6 and Mane et al 9 However Dasgupta et al 12 recorded an almost equal proportion of neoplastic and non-neoplastic lesions. (Table 5)…”

Section: Discussionsupporting

confidence: 92%

“…In the present study, benign neoplastic lesions (54.17%) marginally outnumbered the malignant neoplastic lesions (45.83%). Similar findings were noted in the study by Khan et al 11 But Tondon et al 10 and Mane et al 9 reported a higher proportion of benign neoplastic lesions (73.53% and 71.43% respectively) compared to malignant lesions (26.47% and 28.57% respectively).…”

Section: Neoplastic Lesions Of Sinonasal Tractsupporting

confidence: 86%

“…8 In the study conducted by Mane et al, the most (H&E, 400X) Inset: GMS stain highlights the thin, branching hyphae common age group was 21-30 years (35 cases, 27.78%) followed by 31-40 years (31 cases, 24.60%). 9 Male to female ratio of 1.39:1 was calculated in this study. Similar findings of male preponderance were observed in studies conducted by Tondon et al, 10 Khan et al 11 and Kulkarni et al 6 We observed higher frequency of non-neoplastic lesions (80.33%) in comparison with neoplastic lesions (19.67%).…”

Section: Discussionmentioning

confidence: 95%

“…The most common nonneoplastic lesion was sinonasal polyp (85.72%) followed by fungal rhinosinusitis (5.10%), epidermal inclusion cyst (4.08%), rhinosporidiosis (2.04%), lepromatous leprosy (1.02%), chronic nonspecific inflammation (1.02%) and arteriovenous malformation (1.02%). Studies conducted by Dasgupta et al, 12 Pushpalatha et al 13 and Mane et al 9 also noted that sinonasal polyp was the most common nonneoplastic lesion. Other non-neoplastic lesions like fungal rhinosinusitis, rhinosporidiosis and epidermal inclusion cyst showed varying frequencies.…”

Section: Non-neoplastic Lesions Of Sinonasal Tractmentioning

confidence: 89%

“…According to this study, the mean age of presentation of patients diagnosed with fungal rhinosinusitis was 62.4 years wit h female predominance (M:F ratio 1:1.5). Mane et al 9 reported the mean age of presentation of fungal rhinosinusitis was 50.7 years with male preponderance (2:1). This suggests that fungal rhinosinusitis mainly affects the elderly.…”

Section: Fungal Rhinosinusitismentioning

confidence: 99%

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Histopathological study of lesions of nasal cavity and paranasal sinuses

Kulkarni¹,

Shetty²,

Pathak³

2020

IJPO

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The nasal cavity and paranasal sinuses are exposed to many environmental pollutants and pathogens. Exposure to such influences can lead to a variety of lesions primarily affecting the sinonasal tract. The aim of this study was to find out the incidence, age and sex distribution and to enlist the different types of lesions of the nasal cavity and paranasal sinuses. Materials and Methods: A study of 122 cases was conducted over a 2 year period. Both retrospective and prospective cases were included in the study. All relevant clinical details, tissue sections with H&E, special stains and IHC stains were done whenever necessary. Result: Out of 122 cases, 98 non-neoplastic cases and 24 neoplastic cases were diagnosed. Maximum n on-neoplastic cases were detected in the third and fourth decade. Benign lesions were commonly noted in fourth and seventh decade. Malignant lesions of sinonasal tract commonly afflicted patients of 61 to 70 years of age. Non-neoplastic and benign lesions showed male predominance. Female preponderance was noted in malignant lesions of sinonasal tract. Among non-ne oplastic lesions, sinonasal polyp (84 cases) was most prevalent. Maximum proportion of benign lesions were diagnosed as hemangioma (6 cases) and sinonasal papilloma (5 cases). Among malignant neoplastic lesions, 4 cases were of squamous cell carcinoma and 3 cases were of malignant melanoma. Conclusion:A variety of lesions with overlapping clinical features can affect the sinonasal tract. Histopathology remains the gold standard for establishing the diagnosis in such cases.

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Section: Discussionsupporting

confidence: 92%

Section: Neoplastic Lesions Of Sinonasal Tractsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 95%

Section: Non-neoplastic Lesions Of Sinonasal Tractmentioning

confidence: 89%

Section: Fungal Rhinosinusitismentioning

confidence: 99%

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Histopathological study of lesions of nasal cavity and paranasal sinuses

Kulkarni¹,

Shetty²,

Pathak³

2020

IJPO

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Clinico-pathological spectrum of sinonasal masses: a tertiary care hospital experience

Maheshwari

Bansal

2017

Int J Otorhinolaryngol Head Neck Surg

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Background: Sinonasal masses (SNM) are a fairly common clinical entity that occurs amongst patients of all age groups. There symptoms and signs frequently overlap, hence a diagnostic dilemma exists. A correct diagnosis is prudent for instituting correct treatment and expecting recovery. The purpose of this retrospective analysis was to decipher and study the various pathologies that present as sinonasal masses.Methods: A retrospective analysis done on 80 patients of SNM who presented to the Department of ENT, Subharti Medical College and Hospital, Meerut from May 2016 to April 2017. Their biodata, clinical profile and histolopathological diagnosis were analyzed. Results: SNM were male predominant and were non-neoplastic in 53 cases (66.25%). Nasal obstruction was the most common presenting feature (71 cases, 88.75%). Nasal polyps are the most commonly encountered SNM. Non-neoplastic SNM were common in the age group of 11 to 40 years. Benign SNM were common during the 2nd to 4th decade of life, while malignant SNM were common from 5th decade onwards.Conclusions: SNM constitute a very wide spectrum of differential diagnoses. They have a male predominance and majority are non-neoplastic. Nasal polyps are the most commonly encountered SNM, seen during 2nd to 4th decade of life, while squamous cell carcinoma is the most commonly encounterd malignancy, generally from 5th decade onwards. Surgery is the treatment of choice.

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Clinicopathological analysis of sinonasal lesions

Thokal¹,

Kulkarni

Sidhewad³

et al. 2022

IJPO

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The sinonasal tract is exposed to a variety of infections, chemical irritants, antigens and trauma giving rise to diverse inflammatory as well as neoplastic lesions. The aim was to study the clinicopathological profile of lesions of nose and paranasal sinuses in this area of western Maharashtra. The study included 59 biopsies/resection specimens received in the department during Jan 2015 to June 2019. Clinical and pathological details were analysed. There were 33 females and 26 males. Out of 59 cases, 46 were nonneoplastic and 13 neoplastic, with 10 benign and three malignant. The most common nonneoplastic lesion was sinonasal polyp (42 cases). Other nonneoplastic lesions included three cases of mucormycosis and one case of rhinosporidiosis. In the benign neoplasms, there were three cases of hemangiomas, two hamartomas, two inverted papillomas with one case each of hidradenoma, angiofibroma and schwannoma. We had three malignant tumors, one case each of, melanoma, poorly differentiated carcinoma and squammous cell carcinoma. Nonneoplastic lesions were much more common than neoplastic ones in the sinonasal tract. Histopathological examination plays an important role in correct diagnosis and management.

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Clinicopathological study of Sinonasal Masses

Cited by 12 publications

References 10 publications

Histopathological study of lesions of nasal cavity and paranasal sinuses

Histopathological study of lesions of nasal cavity and paranasal sinuses

Clinico-pathological spectrum of sinonasal masses: a tertiary care hospital experience

Clinicopathological analysis of sinonasal lesions

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