Cloning of cDNAs and molecular characterisation of C-type lectin-like proteins from snake venoms

Abstract

Please cite this article as: Feng, J., Chen, T., Zhou, M., Shaw, C., Cloning of cDNAs and molecular characterisation of C-type lectin-like proteins from snake venoms, Toxicon (2012), doi: 10.1016/ j.toxicon.2012.09.011. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT Research highlights1. cDNA libraries prepared from lyophilised snake venoms.2. Four cDNAs encoding CTLP subunits were cloned from these using a single sense primer. Platelet glycoprotein

Functional recombinant single‑chain variable fragment antibody against Agkistrodon acutus venom

“…Agkistrodon acutus is one of the most common venomous snakes in China and Vietnam (1). A. acutus venom contains metalloproteinases, phospholipase C-type lectin-like proteins and serine proteases (2,3). Snakebites of A. acutus can cause acute reactions, including tissue inflammation, edema, necrosis and hemorrhage, as well as clotting abnormalities, which can induce multiple organ failure (4,5).…”