A novel differential filtering antenna with high selectivity is proposed. The antenna is mainly composed of three different‐size patches, a slot, a pair of differential feeding lines, and a line resonator. An air gap is adopted to improve the impedance bandwidth and the filtering performance. The line resonator helps to generate high common‐mode (CM) rejection. Owing to the parasitic concave and convex patches, the filtering performance and the bandwidth of the antenna are enhanced. The parasitic concave patch affects the lower band‐edge selectivity while the parasitic convex patch influences the upper band‐edge selectivity. In addition, the frequencies of two radiation nulls can be controlled independently to achieve two high sharp roll‐off rates by adjusting the lengths of the parasitic patches. Considerable impedance matching bandwidth is achieved through an aperture coupling. Finally, a prototype of the differential filtering antenna is fabricated and tested. The measured results are in good agreement with the simulated results, showing an impedance bandwidth of 9.9% and an average realized gain of 7.5 dBi. Besides, two filter zero transmissions located at 3.40 and 3.84 GHz produced two radiation nulls.