Clostridium botulinum was named because of association with "sausage poisoning"

Torrens, J.K.

doi:10.1136/bmj.316.7125.151c

Cited by 27 publications

(8 citation statements)

References 3 publications

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“…The disease was associated to the consumption of pork blood sausage and was initially termed sausage poisoning. The name botulism was coined later in the second half of the 19th century from the Latin word "botulus" meaning sausage [14,15]. Botulism was not reported or misdiagnosed during this period in Alsace which is close to the Wurtenberg region and where the consumption of pork sausages was common.…”

Section: Foodborne Botulismmentioning

confidence: 99%

Human Botulism in France, 1875–2016

Rasetti-Escargueil

Lemichez

Popoff

2020

Toxins

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Botulism is a rare but severe disease which is characterized by paralysis and inhibition of secretions. Only a few cases had been reported at the end of the 19th century in France. The disease was frequent during the second world war, and then the incidence decreased progressively. However, human botulism is still present in France with 10–25 cases every year. Food-borne botulism was the main form of botulism in France, whereas infant botulism (17 cases between 2004 and 2016) was rare, and wound and inhalational botulism were exceptional. Type B was the prevalent botulism type and was mainly due to consumption of home-made or small-scale preparations of cured ham and to a lesser extent other pork meat products. In the recent period (2000–2016), a wider diversity of botulism types from various food origin including industrial foods was reported. Severe cases of type A and F botulism as well as type E botulism were more frequent. Albeit rare, the severity of botulism justifies its continued surveillance and recommendations to food industry and consumers regarding food hygiene and preservation practices.

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Section: Foodborne Botulismmentioning

confidence: 99%

Human Botulism in France, 1875–2016

Rasetti-Escargueil

Lemichez

Popoff

2020

Toxins

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“…Further publications in the 19th century by Kerner and various other authors added nothing substantial to Kerner's early observations. The sausage poisoning was named “botulism” after the Latin word botulus , meaning sausage 10. The next and most important scientific step was the discovery of botulinum toxin–producing bacteria in 1895 by the Microbiologist Emile Pierre Marie van Ermengem.…”

Section: Botulism Research After Kernermentioning

confidence: 99%

Historical notes on botulism,Clostridium botulinum, botulinum toxin, and the idea of the therapeutic use of the toxin

Erbguth

2004

Mov Disord.

190

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Food-borne botulism probably has accompanied mankind since its beginning. However, we have only few historical sources and documents on food poisoning before the 19th century. Some ancient dietary laws and taboos may reflect some knowledge about the life-threatening consumption of poisoned food. One example of such a dietary taboo is the 10th century edict of Emperor Leo VI of Byzantium in which manufacturing of blood sausages was forbidden. Some ancient case reports on intoxications with Atropa belladonna probably described patients with food-borne botulism, because the combination of dilated pupils and fatal muscle paralysis cannot be attributed to an atropine intoxication. At the end of the 18th century, some well-documented outbreaks of "sausage poisoning" in Southern Germany, especially in Württemberg, prompted early systematic botulinum toxin research. The German poet and district medical officer Justinus Kerner (1786-1862) published the first accurate and complete descriptions of the symptoms of food-borne botulism between 1817 and 1822. Kerner did not succeed in defining the suspected "biological poison" which he called "sausage poison" or "fatty poison." However, he developed the idea of a possible therapeutic use of the toxin. Eighty years after Kerner's work, in 1895, a botulism outbreak after a funeral dinner with smoked ham in the small Belgian village of Ellezelles led to the discovery of the pathogen Clostridium botulinum by Emile Pierre van Ermengem, Professor of bacteriology at the University of Ghent. The bacterium was so called because of its pathological association with the sausages (Latin word for sausage = "botulus") and not-as it was suggested-because of its shape. Modern botulinum toxin treatment was pioneered by Alan B. Scott and Edward J. Schantz.

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“…Botulinum neurotoxin A (BoNTA) was discovered in the early 1900s, receiving its first U.S. Food and Drug Administration (FDA) approval in 1989 and is now used to treat a multitude of conditions, both functional and cosmetic. [1][2][3][4] Pregnancy and lactation are relative contraindications for botulinum toxin injections. Owing to the elective nature of the injections for aesthetics, most patients and physicians have elected to delay treatment during pregnancy and nursing periods.…”

Section: Introductionmentioning

confidence: 99%

Case Series of Botulinum Toxin Administered to Pregnant Patients and Review of the Literature

Cardon

Smith

Cerrati

2021

Facial Plastic Surgery & Aesthetic Medicine

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Objective: To evaluate a case series of patients who received medically necessary botulinum toxin during pregnancy. Materials and Methods: Retrospective chart review of three patients who underwent repeated intralaryngeal injections of botulinum toxin during pregnancy. Chart reviews were also conducted on the children to further evaluate the safety. Results: No evidence of harm to the mothers or fetuses were found in our series, including data from pregnancy and birth records using standard measures of gestation, APGAR scores, neonatal intensive care unit stay, and time until discharge. Clinical data for 3-5 years were available for the children. No evidence of muscular weakness was noted and all diagnoses were listed. Conclusion: Botulinum toxin injection for functional airway issues was not associated with any adverse effects to the mother or fetus during pregnancy in any of the cases reviewed. We recommend further investigation to evaluate the current contraindication of elective botulinum toxin use in pregnancy.

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Clostridium botulinum was named because of association with "sausage poisoning"

Cited by 27 publications

References 3 publications

Human Botulism in France, 1875–2016

Human Botulism in France, 1875–2016

Historical notes on botulism,Clostridium botulinum, botulinum toxin, and the idea of the therapeutic use of the toxin

Case Series of Botulinum Toxin Administered to Pregnant Patients and Review of the Literature

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