Smart5Grid exploits the robustness and flexibility enabled by the 5-th generation (5G) mobile network technology to contribute an open and adaptable platform for reliable testing, validation, and operation of Network Applications (NetApps), addressing the challenges of the Renewable Energy Sources (RES) production and those of the operation of the active power distribution ecosystem, in particular. Smart5Grid aims to support current energy sector and future smart grid stakeholders through the adaptation of 5G networks and the support of the respective NetApps that will be developed and validated on real power grid facilities. Smart5Grid intends to provide a more secure, flexible, efficient, scalable and real-time communication framework for modern smart grids. Through remote inspection and control of automatically delimited working areas, the capabilities of the created Smart5Grid 5G platform will facilitate the improvement of working conditions for power grid maintenance crews and inspection workers. In this paper, we presented the methodology of the Smart5Grid project, which will enable remote inspections in high-risk areas and real-time execution by supporting various distribution network applications and providing accurate results and information on the operational condition of power grid assets via augmented reality. If maintenance work is undertaken, realtime control will be enabled to support working procedures remotely and automatically, without putting employees in potentially harmful conditions.