Entanglement entropy (EE), a fundamental conception in quantum information for characterizing entanglement, has been extensively employed to explore quantum phase transitions (QPTs). Although the conventional single-site mean-field (MF) approach successfully predicts the emergence of QPTs, it fails to include any entanglement. Here, for the first time, in the framework of a cluster MF treatment, we extract the signature of EE in the bosonic superfluid-insulator (SI) transitions. We consider a trimerized Kagomé lattice of interacting bosons, in which each trimer is treated as a cluster, and implement the cluster MF treatment by decoupling all inter-trimer hopping. In addition to superfluid and integer insulator phases, we find that fractional insulator phases appear when the tunneling is dominated by the intra-trimer part. To quantify the residual bipartite entanglement in a cluster, we calculate the second-order Rényi entropy, which can be experimentally measured by quantum interference of many-body twins. The second-order Rényi entropy itself is continuous everywhere, however, the continuousness of its first-order derivative breaks down at the phase boundary. This means that the bosonic SI transitions can still be efficiently captured by the residual entanglement in our cluster MF treatment. Besides to the bosonic SI transitions, our cluster MF treatment may also be used to capture the signature of EE for other QPTs in quantum superlattice models.