Cluster of oral atypical Candida albicans isolates in a group of human immunodeficiency virus-positive drug users

Boerlin, Patrick; Boerlin-Petzold, F; Durussel, Christian; Addo, Michelle Yaa; Pagani, Jean‐Luc; Chave, Jean-Philippe; Billé, Jacques

doi:10.1128/jcm.33.5.1129-1135.1995

Cited by 87 publications

(60 citation statements)

References 24 publications

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“…In the last few years, several research groups have reported the recovery of many atypical isolates of C. albicans in clinical samples. 2,[6][7][8][9][10] Atypical isolates, such as C. africana, differ from most typical C. albicans strains because one or more phenotypic characteristics are clearly different. These atypical strains are often difficult to recognise by routine methods and they may represent variants of C. albicans or even new species as C. dubliniensis.…”

Section: Resultsmentioning

confidence: 99%

Morphological, biochemical and molecular characterisation of the first Italian Candida africana isolate

Romeo

Criseo

2009

Mycoses

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One atypical isolate of the pathogenic yeast Candida albicans was isolated from an Italian patient with vulvovaginitis. The strain, germ tube positive and chlamydospore-negative showed white-thin turquoise colonies on Candida ID 2 medium. The yeast was identified as Candida africana by using morphological and biochemical tests. On the basis of the molecular results obtained in this study as well as in other studies, C. africana cannot be yet considered as a new species of Candida. It is possible that C. africana represents a new variant of C. albicans like the well-known Candida stellatoidea. To our knowledge, this is the first isolation of C. africana in Italy.

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Section: Resultsmentioning

confidence: 99%

Morphological, biochemical and molecular characterisation of the first Italian Candida africana isolate

Romeo

Criseo

2009

Mycoses

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“…These findings are in accordance with other studies. 5,16 As phenotypic assays may demonstrate different results in identifying C. dubliniensis we also performed PCR with speciesspecific primers for C. dubliniensis. In our test conditions all suspected isolates were positive with primers DUBF and DUBR in accordance with Donnelly et al 18 We found four (11.4%) isolates in our patient group as C. dubliniensis.…”

Section: Discussionmentioning

confidence: 99%

Detection of Candida dubliniensis in oropharyngeal samples of Turkish HIV‐positive patients

Tekelı

Koyuncu

Dolapçı

et al. 2005

Mycoses

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The incidence of Candida dubliniensis in immunocomprimised patients in Turkey has not yet been determined. In this study the presence of C. dubliniensis in oral rinse samples of human immunodeficiency virus (HIV)-positive patients and healthy controls were investigated. Phenotypic tests like inability of growth at 45 degrees C, colony formation on Staib agar, intracellular beta-D-glucosidase activity, carbohydrate assimilation profiles and polymerase chain reaction with species-specific primers (DUBF and DUBR) were carried out for differentiation of C. dubliniensis. Of the 35 patients, four (11.4%) had C.dubliniensis in their oral cavity. Antifungal susceptibility testing of these C. dubliniensis isolates showed fluconazole MICs ranging from <0.06 to 32 microg ml(-1) and amphotericin B from <0.06 to 0.25 microg ml(-1). One isolate was dose-dependently susceptible to fluconazole (32 microg ml(-1)). This study demonstrates C. dubliniensis in HIV-positive patients from Turkey.

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“…Atypical candidal isolates have recently been reported from the oropharyngeal region of HIV-seropositive drug users(5). Despite showing similarities with C. albicans, namely a positive germ-tube test and the production of chlamydospores, such isolates showed abnormal sugar assimilation profiles that did not correspond to any known yeast species.…”

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confidence: 99%

Isolation of C. dubliniensis from insulin‐using diabetes mellitus patients

Willis¹,

Coulter

Sullivan

et al. 2000

J Oral Pathology Medicine

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The identification of the novel candidal species, C. dubliniensis, from oral swab studies of HIV-seropositive and -seronegative individuals has led to speculation that such a species may also reside in the oral cavity of other patient groups. In this study involvement of the newly described species, C. dubliniensis, was investigated in oral carriage and disease in 414 insulin-using diabetes mellitus patients. Seventy-seven percent of the diabetic patients carried candidal species in the oral cavity. C. albicans was the most commonly identified candidal species. This was followed by C. dubliniensis, which was isolated on 64 occasions. Colonisation with multiple candidal species was common, and C. dubliniensis was present in both carriage and disease states. Seven patients without signs of oral disease had C. dubliniensis isolated as the sole candidal species, while the same species was associated with various forms of oral candidosis in six patients.

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Cluster of oral atypical Candida albicans isolates in a group of human immunodeficiency virus-positive drug users

Cited by 87 publications

References 24 publications

Morphological, biochemical and molecular characterisation of the first Italian Candida africana isolate

Morphological, biochemical and molecular characterisation of the first Italian Candida africana isolate

Detection of Candida dubliniensis in oropharyngeal samples of Turkish HIV‐positive patients

Isolation of C. dubliniensis from insulin‐using diabetes mellitus patients

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