CMKLR1 senses chemerin/resolvin E1 to control adipose thermogenesis and modulate metabolic homeostasis

Zhao, Zewei; Liu, Siqi; Qian, Bingxiu; Lin, Zhou; Shi, Jianglin; Liu, Junxi; Xu, Lin; Yang, Zhonghan

doi:10.1016/j.fmre.2022.06.014

Cited by 3 publications

(2 citation statements)

References 46 publications

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“…And this future is being encroached upon by all kinds of encroachments. Among them are such spawns of the "cunning of reason" (Hegel) of the latest technologies as eugenics, transhumanism, and biohacking [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

RETRACTED: The role of physical education in preserving the integrity of human existence

Byankina,

Manikovskaya,

Stukova

2024

BIO Web Conf.

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The problems of preserving existentiality as a proper human way of being, human authenticity and identity arise in the wake of the latest technologies, instrumentalisation of human life and digitalisation of all spheres of society. Consideration of human integrity from the point of view of kalokagatia is presented in the article from the perspective of physical culture and sport. The mission of physical culture is understood and justified as ensuring the harmonious integrity of existentiality, human existence in its fundamental, deep ontological specificity. Harmonic integrity of a person is considered from the point of view of semantic differential of subjectivity of its research in three categories of persons: students, athletes, coaches. The meaning of harmonic integrity is also seen in the concept that actualises the idea of a special quality of the national resource - human capital, understood as a resource of skills and competences, as well as knowledge, on the basis of which human abilities are developed.

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Section: Introductionmentioning

confidence: 99%

RETRACTED: The role of physical education in preserving the integrity of human existence

Byankina,

Manikovskaya,

Stukova

2024

BIO Web Conf.

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“…An obesogenic diet increases chemerin secretion from brown adipocytes, while cold stimulation caused the opposite [ 118 , 119 ]. Chemerin might contribute to temperature regulation, given that its overexpression decreased whole body and brown adipose tissue temperature in mice [ 120 ]. Chemerin overexpression additionally impaired metabolic homeostasis and induced glucose intolerance.…”

Section: Potential Role Of Chemerin In Metabolic and Cardiovascular D...mentioning

confidence: 99%

The Role of Chemerin in Metabolic and Cardiovascular Disease: A Literature Review of Its Physiology and Pathology from a Nutritional Perspective

Tan

Danser

et al. 2023

Nutrients

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Chemerin is a novel adipokine that plays a major role in adipogenesis and lipid metabolism. It also induces inflammation and affects insulin signaling, steroidogenesis and thermogenesis. Consequently, it likely contributes to a variety of metabolic and cardiovascular diseases, including atherosclerosis, diabetes, hypertension and pre-eclampsia. This review describes its origin and receptors, as well as its role in various diseases, and subsequently summarizes how nutrition affects its levels. It concludes that vitamin A, fat, glucose and alcohol generally upregulate chemerin, while omega-3, salt and vitamin D suppress it. Dietary measures rather than drugs acting as chemerin receptor antagonists might become a novel tool to suppress chemerin effects, thereby potentially improving the aforementioned diseases. However, more detailed studies are required to fully understand chemerin regulation.

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Inflammation and resolution in obesity

Soták,

Clark,

Suur

et al. 2024

Nat Rev Endocrinol

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CMKLR1 senses chemerin/resolvin E1 to control adipose thermogenesis and modulate metabolic homeostasis

Cited by 3 publications

References 46 publications

RETRACTED: The role of physical education in preserving the integrity of human existence

RETRACTED: The role of physical education in preserving the integrity of human existence

The Role of Chemerin in Metabolic and Cardiovascular Disease: A Literature Review of Its Physiology and Pathology from a Nutritional Perspective

Inflammation and resolution in obesity

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