CMOS-based chemical microsensors

Hierlemann, Andreas; Baltes, H.

doi:10.1039/b208563c

Cited by 117 publications

(56 citation statements)

References 125 publications

(233 reference statements)

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“…Fig. 2b shows a scheme of CMOS-based thermopile consisting of a dielectric membrane and aluminum/ polysilicon thermocouples [9]. The Seebeck coefficient is equal to 111 mV/K.…”

Section: Catalytic Sensorsmentioning

confidence: 99%

Detection of Gaseous Compounds with Different Techniques

Mikołajczyk

Bielecki

Stacewicz

et al. 2016

Metrology and Measurement Systems

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Sensing technology has been developed for detection of gases in some environmental, industrial, medical, and scientific applications. The main tasks of these works is to enhance performance of gas sensors taking into account their different applicability and scenarios of operation. This paper presents the descriptions, comparison and recent progress in some existing gas sensing technologies. Detailed introduction to optical sensing methods is presented. In a general way, other kinds of various sensors, such as catalytic, thermal conductivity, electrochemical, semiconductor and surface acoustic wave ones, are also presented. Furthermore, this paper focuses on performance of the optical method in detecting biomarkers in the exhaled air. There are discussed some examination results of the constructed devices. The devices operated on the basis of enhanced cavity and wavelength modulation spectroscopies. The experimental data used for analyzing applicability of these different sensing technologies in medical screening. Several suggestions related to future development are also discussed.

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“…Fig. 2b shows a scheme of CMOS-based thermopile consisting of a dielectric membrane and aluminum/ polysilicon thermocouples [9]. The Seebeck coefficient is equal to 111 mV/K.…”

Section: Catalytic Sensorsmentioning

confidence: 99%

Detection of Gaseous Compounds with Different Techniques

Mikołajczyk

Bielecki

Stacewicz

et al. 2016

Metrology and Measurement Systems

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“…For an ISFET operating in the saturation region, the drain current is given by (1) where is a process-dependant constant, is the channellength modulation factor, and and are the width and length of the channel. and are the source and drain terminal voltages, and is the applied reference electrode voltage.…”

Section: B the Analogue Subsystemmentioning

confidence: 99%

“…CMOS is the dominant technology for system-on-chip devices, and for integrated circuits in general. In order to exploit the ubiquitous nature of CMOS chips, there have been many initiatives to fabricate chemical sensors in compatible technologies [1]. Most notably, a gas sensor which includes micro-machined resonating beams and digital interface electronics, has been integrated into a single CMOS chip [2].…”

Section: Introductionmentioning

confidence: 99%

A System-on-Chip Digital pH Meter for Use in a Wireless Diagnostic Capsule

Hammond

Ali

Cumming

2005

IEEE Trans. Biomed. Eng.

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Abstract-This paper describes the design and implementation of a system-on-chip digital pH meter, for use in a wireless capsule application. The system is organized around an 8-bit microcontroller, designed to be functionally identical to the Motorola 6805. The analog subsystem contains a floating-electrode ISFET, which is fully compatible with a commercial CMOS process. On-chip programmable voltage references and multiplexors permit flexibility with the minimum of external connections. The chip is designed in a modular fashion to facilitate verification and component re-use. The single-chip pH meter can be directly connected to a personal computer, and gives a response of 37 bits/pH, within an operating range of 7 pH units.

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“…to interacts (i.e., recognizes or binds) with an analyte [3]. A biosensor usually consists of three elements; a biorecognition, biotransducer, and an electronic system that include a processor, signal amplifier, and display [4,5]. The recognition part often termed as a bioreceptor, which exploits biomolecules as receptors to interact with a specific analyte.…”

Section: Introductionmentioning

confidence: 99%

Recent Advances and Applications of Biosensors in Novel Technology

Rajpoot¹

2017

Biosens J

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In recent time, several novel biosensors such as enzyme based, immunosensors, tissue-based, DNA biosensors, piezoelectric, and thermal biosensors have been explored with high sensitivity by many research groups. These biosensors exhibit many essential benefits, including operational simplicity, remarkable sensitivity, low-cost instrumentation, the potential of automation, inherent miniaturization. They have offered elegant paths for the detection of even trace amounts of analytical agents of biological significance existing from macromolecules (e.g., disease biomarkers and antigens) and small molecules (e.g., natural toxins and haptens) to cells, viruses, and bacteria. Many electrochemical techniques viz., amperometry and voltammetry, photoelectrochemistry, electrochemiluminescence, impedance, piezoelectricity, potentiometry, alternating current electrohydrodynamics, and field-effect transistor have been utilized in the development of immunoassays to attain high sensitivity for electrochemical signal transduction. Recent developments in biological methods and instrumentation after using fluorescence tag to various nanocarriers such as nanoparticles, nanowires, nanotubes, etc. have improved the sensitivity of biosensors. Utilization of nucleotides/aptamers, affibodies, molecule imprinted polymers, and peptide arrays offer great tools to prepare advanced biosensors. Merging of nanotechnology with biosensor systems enhanced the diagnostic capability. This review gives an outline of the advances in biosensors technology relating biomedical sciences.

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CMOS-based chemical microsensors

Cited by 117 publications

References 125 publications

Detection of Gaseous Compounds with Different Techniques

Detection of Gaseous Compounds with Different Techniques

A System-on-Chip Digital pH Meter for Use in a Wireless Diagnostic Capsule

Recent Advances and Applications of Biosensors in Novel Technology

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