Co-activation differences in lower limb muscles between asymptomatic controls and those with varying degrees of knee osteoarthritis during walking

Hubley‐Kozey, Cheryl L.; Hill, Nicholas A.; Rutherford, Derek; Dunbar, Michael J.; Stanish, William D.

doi:10.1016/j.clinbiomech.2009.02.005

Cited by 118 publications

(77 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This proposal will also allow evaluation of stride-to-stride CAI variability in relation to stride-to-stride velocity, cadence and amplitude variability (since all of them would be controlled). Notwithstanding, it is clear that results from this study do not question the results for other pathologies at which a more defined pattern seems to have been described, for instance in knee osteoarthritis (Hubley-Kozey et al, 2009) or stroke (Lamontagne et al, 2000).…”

Section: Discussionsupporting

confidence: 48%

“…The analysis of antagonist CAI during gait has been chiefly focused on the study of physiological aging (Hortobágyi et al, 2009;Peterson and Martin, 2010;Schmitz et al, 2009) and on some pathologies like stroke (Lamontagne et al, 2000), or knee osteoarthritis (Hubley-Kozey et al, 2009). Some of the above mentioned studies, and others (for example, Mian et al, 2006), evaluated CAI on thigh muscles.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Antagonist muscle co-activation during straight walking and its relation to kinematics: Insight from young, elderly and Parkinson's disease

et al. 2012

View full text Add to dashboard Cite

Increased antagonist muscle co-activation of the lower limb during walking seems to be an adaptive process to the physiological changes of aging, in order to gain joint stability. In the healthy subjects this view seems to be reinforced by the fact that the co-activation index (CAI) increases when the gait is faster. The few reports on antagonist coactivation in Parkinson's disease (PD) patients indicate that they have larger co-activation than the healthy elderly, supporting the idea of the stabilization role of CAI during gait, as postural instability is a cardinal feature of PD. However it has also been reported that there is a reduction of the CAI when increasing velocity in PD or normal elderly. This questions the role of coactivation in stabilization during increased velocity. In this study we have analyzed the gait of healthy subjects (young and elderly), and PD patients (with and without freezing of gait, FOG) in order to better understand the relation between co-activation and gait kinematics, and to gain insight into the pathological changes associated with FOG in PD. We used Multiple Linear Regression models to study the relationship in shank muscles between CAI, velocity and cadence. Our results indicate that, for all groups of interest, the relationship between co-activation and the kinematics of gait is poor, due to the high degree of variability, questioning the explanatory value of the index.

show abstract

Section: Discussionsupporting

confidence: 48%

Section: Discussionmentioning

confidence: 99%

Antagonist muscle co-activation during straight walking and its relation to kinematics: Insight from young, elderly and Parkinson's disease

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Hubley- Kozey et al (2009) suggested that early stages of knee osteoarthritis lead to lateral co-contraction, compensating for medial problems, whereas later stages of osteoarthritis induce more "general co-activity" (p. 411; cf. also Heiden et al, 2009).…”

Section: Co-contractionmentioning

confidence: 99%

Determinants of co-contraction during walking before and after arthroplasty for knee osteoarthritis

Fallah-Yakhdani¹,

Bafghi²,

Meijer³

et al. 2012

Clinical Biomechanics

View full text Add to dashboard Cite

Background: Knee osteoarthritis patients co-contract in knee-related muscle pairs during walking. The determinants of this co-contraction remain insufficiently clear. Methods: A heterogeneous group of 14 patients was measured before and one year after knee arthroplasty, and compared to 12 healthy peers and 15 young subjects, measured once. Participants walked on a treadmill at several imposed speeds. Bilateral activity of six muscles was registered electromyographically, and cocontraction time was calculated as percentage of stride cycle time. Local dynamic stability and variability of sagittal plane knee movements were determined. The surgeon's assessment of alignment was used. Preoperatively, multivariate regressions on co-contraction time were used to identify determinants of cocontraction. Post-operatively it was assessed if predictor variables had changed in the same direction as co-contraction time. Findings: Patients co-contracted longer than controls, but post-operatively, differences with the healthy peers were no longer significant. Varus alignment predicted co-contraction time. No patient had post-operative varus alignment. The patients' unaffected legs were more unstable, and instability predicted co-contraction time in both legs. Post-operatively, stability normalised. Longer unaffected side co-contraction time was associated with reduced affected side kinematic variability. Post-operatively, kinematic variability had further decreased. Interpretations: Varus alignment and instability are determinants of co-contraction. The benefits of cocontraction in varus alignment require further study. Co-contraction probably increases local dynamic stability, which does not necessarily decrease the risk of falling. Unaffected side co-contraction contributed to decreasing affected side variability, but other mechanisms than co-contraction may also have played a role in decreasing variability.

show abstract

“…In addition, muscle endurance rather than strength may be a potent determinant of abnormal joint loading [31] . Alignment and muscle action in knee osteoarthritis [36] Differences in muscle activity between cases with osteoarthritis and healthy cases [7,34,78] Hamstring-quadriceps muscle balance in knee osteoarthritis [9,65] Impact of cyclic concentric and eccentric submaximal muscle loading [5] Interlimb symmetry and co-contraction in knee osteoarthritis [61] Knee muscle activation during sit-to-stand in knee osteoarthritis [26,43,86] Knee muscle activation during walking [35,39,41,57,60,64,69,72,73,74,75] Knee extensor power and mobility in knee osteoarthritis [30] Morphological changes in vastus medialis in knee osteoarthritis [10,22] Motor unit properties in knee osteoarthritis [49] Motor control/dysfunction in knee osteoarthritis [25,37,54] Muscle afferent neurons and osteoarthritis [24] Muscle contractile deficits [9,20,85] Muscle cross-sectional areas and knee abnormalities [23] Muscle inflammation and walking [19,27] Muscle strength and inflammation in knee osteoarthritis in older women [81] Muscle strength and proprioception [18] Neuromuscular adaptations during stepping [16] Neuromuscular ...…”

Section: Discussionmentioning

confidence: 99%

“…Muscle weakness or imbalances that may arise consequent to injury, may thus prove harmful to the physiology of the adjacent joints and others over time, if the muscle dysfunction is not corrected optimally. Hubley-Kozey et al [41] concluded that the magnitude of the co-activity measures assessed for four medial and lateral knee muscle pairs over initial stance was partially indicative of the severity of the prevailing knee osteoarthritis pathology.…”

Section: Specific Findingsmentioning

confidence: 99%

Muscle Function during Selected Weight-Bearing Activities in Adults with Knee Osteoarthritis- A Narrative Overview

Marks¹

2016

International Journal of Orthopaedics

View full text Add to dashboard Cite

Co-activation differences in lower limb muscles between asymptomatic controls and those with varying degrees of knee osteoarthritis during walking

Cited by 118 publications

References 28 publications

Antagonist muscle co-activation during straight walking and its relation to kinematics: Insight from young, elderly and Parkinson's disease

Antagonist muscle co-activation during straight walking and its relation to kinematics: Insight from young, elderly and Parkinson's disease

Determinants of co-contraction during walking before and after arthroplasty for knee osteoarthritis

Muscle Function during Selected Weight-Bearing Activities in Adults with Knee Osteoarthritis- A Narrative Overview

Contact Info

Product

Resources

About