Co-existent breast and renal cancer

Abstract

The concomitant presence of breast cancer with one or more other types of cancer such as colon, vulva, lung, larynx, liver, uterus and kidneys has been presented in the literature. However, synchronous breast and renal cancer is very uncommon. Herein we present a woman with synchronous breast and renal cancer, and review the literature. A 77-year-old post-menopausal woman was admitted to our clinic complaining of left sided breast mass. On physical examination, there was a 3 cm palpable mass in the upper outer quadrant of the left breast along with a conglomerate of lymph nodes in the left axilla. Ultrasonography and mammography showed a 3 cm solid, hypoechoic mass in the upper outer quadrant and left axillary lymphadenopathy. The tru-cut biopsy of the lesion revealed invasive ductal carcinoma. The bone scintigraphy, thoracic and cranial computerized tomographies were normal. The abdominal computerized tomography identified a 3x3 cm solid renal mass with heterogeneous contrast enhancement in the posterior segment of the lower pole, which was suspicious for renal cell carcinoma. Breast conserving surgery and axillary lymph node dissection was performed, and the pathology specimen demonstrated invasive ductal carcinoma. The patient was discharged on postoperative day 5. Three weeks later partial nephrectomy was performed by urology department for the solid renal mass, and the pathology result showed clear cell-renal carcinoma with Fuhrman grade 3. The patient is being followed-up for renal carcinoma, and underwent radiotherapy for breast cancer. Hormonotherapy for breast cancer is still continuing.

Synchronous invasive ductal breast cancer with clear cell renal carcinoma: a rare case report with review of literature

“…In the treatment of renal cell carcinoma with multiple tumors, several factors should be interpreted, including the tumor stage, evaluation for the presence of metastasis, and whether the kidney tumor is accessible for operation. Mostly, the choice of treatment is the resection of tumors simultaneously [7] . In the follow-up, to ensure the lack of renal cell cancer recurrence, several examinations like urine analysis, general examination, palpation of lymph nodes every 2 years, and cystoscopy in 10 years intervals can be done [17] .…”

“…Although renal cell carcinoma is a well-known kidney cancer that comprises almost 2%–3% of the entire cancer incidences in adults, the co-occurrence of breast cancer with other types like colon, lung, liver, vulva, larynx, kidneys, and uterus cancers is not rare. In addition, synchronous and metachronous cancer between kidneys and other related organs has also been reported1,7. While the association of renal cancer with breast carcinoma is a rare entity8.…”

EfficientNet family U-Net models for deep learning semantic segmentation of kidney tumors on CT images

“…These may include blood tests to assess kidney function and identify any markers of cancer, such as elevated levels of certain proteins, and imaging studies, such as CT or MRI scans, to evaluate the size and location of the tumor and identify any metastases. Follow-up tests include urine analysis, general examinations, lymph node palpations every 2 years, and cystoscopies every 10 years to check for the absence of renal cell carcinoma recurrence (Beisland et al, 2006;Üreyen et al, 2015;Abdelrahman and Viriri, 2022;Bapir et al, 2022).…”

Association study between intestinal flora and renal malignancy based on genome-wide association analysis data

“…Early diagnosis and prompt treatment are critical to improving patient survival 10 . Overall, renal malignancy is a worrisome disease, but as medical technology continues to develop and advance, it is hoped that more effective treatment options will be available for patients to improve survival rates and quality of life 11,12 . However, prevention remains one of the most important tools.…”