Co-Occurrence of Autistic Spectrum Disorder and Childhood-Onset Schizophrenia

Hatila, Sangeeta; Solanki, Gunjan

doi:10.4088/pcc.19l02515

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A diagnosis of paranoid schizophrenia comorbid with ASD was performed. In this case, there was a history of birth insult, which is underestimated as a possible risk factor for both ASD and SCZ ( 119 ).…”

Section: Clinical Course Of Asd and Sczmentioning

confidence: 93%

See 1 more Smart Citation

Recognizing Psychosis in Autism Spectrum Disorder

et al. 2022

View full text Add to dashboard Cite

There is strong evidence for the existence of a high comorbidity between autism and psychosis with percentages reaching up to 34. 8% and several significant implications for treatment and prognosis of these patients. However, the identification of comorbid psychosis in patients with Autism Spectrum Disorder represents a complex challenge from a psychopathological point of view, in particular in patients with greater deficits in verbal communication. Intercepting the onset of a psychotic breakdown in autism may be very difficult, both disorders in fact occur along a phenotypic continuum of clinical severity and in many cases, psychotic symptoms are present in an attenuated form. In this paper, we reviewed the available scientific literature about comorbidity between psychosis and autism, focusing our attention on four specific dimensions: delusions, hallucinations, negative symptoms, and clinical course. The aim of this paper is to provide clinical tools to identify these psychotic phenomena in autistic patients, even when they occur in their attenuated form.

show abstract

Section: Clinical Course Of Asd and Sczmentioning

confidence: 93%

“…In a clinical case reported by Hatila and Solanki ( 119 ), the patient (an Indian 26 years old male) was diagnosed with ASD ( DSM-IV-TR criteria) at the age of 4. Then, at the age of 6, he was sent to a special school, from which he was later withdrawn due to aggressive behavior.…”

Section: Clinical Course Of Asd and Sczmentioning

confidence: 99%

Recognizing Psychosis in Autism Spectrum Disorder

et al. 2022

View full text Add to dashboard Cite

show abstract

The Triad of Childhood-Onset Schizophrenia, Autism Spectrum Disorder, and Catatonia: A Case Report

O'Sullivan

2023

Schizophrenia Bulletin

View full text Add to dashboard Cite

Childhood-onset schizophrenia (COS) is a rare and severe form of schizophrenia with an estimated prevalence of 1/10,000. Schizophrenia and Autism spectrum disorder (ASD) have shared phenotypic features and shared genetic etiology. There is growing research surrounding the co-occurrence of psychomotor syndromes like catatonia with neurodevelopmental disorders like ASD or psychiatric disorders like schizophrenia. In 2013, Shorter and Wachtel described a phenomenon of the ‘Iron Triangle’ where COS, ASD, and catatonia often co-occur. The Iron Triangle theory is based on observation of historical case literature, which showed that all three diagnoses in the Iron Triangle were routinely assigned to children and adolescents. The pattern of this “Iron Triangle” suggests there may be a single underlying pathology resulting in a unique mixed form of catatonia, autism, and psychosis. We describe the case of a boy with sequential development of COS, ASD, and catatonia who also has syndromic facial and musculoskeletal features. This case highlights overlapping diagnostic features of these three disorders and can help us better understand how “hidden” features of catatonia may occur in patients with COS or ASD but go unrecognized, because they are grouped as features under autism/schizophrenia rather than a distinct diagnosis of catatonia. Further study is warranted to elucidate if this phenotypic pattern constitutes a new single diagnosis that is not well understood, an endophenotype of schizophrenia, or if this is the result of phenomenological overlap between catatonia, ASD, and COS.

show abstract

Co-Occurrence of Autistic Spectrum Disorder and Childhood-Onset Schizophrenia

Cited by 2 publications

References 0 publications

Recognizing Psychosis in Autism Spectrum Disorder

Recognizing Psychosis in Autism Spectrum Disorder

The Triad of Childhood-Onset Schizophrenia, Autism Spectrum Disorder, and Catatonia: A Case Report

Contact Info

Product

Resources

About