Coating of bioactive glass on magnesium alloys to improve its degradation behavior: Interfacial aspects

Yadav, Vivek; Sankar, Mamilla Ravi; Pandey, Lalit M.

doi:10.1016/j.jma.2020.05.005

Cited by 44 publications

(19 citation statements)

References 105 publications

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“…[251] Numerous studies have demonstrated that Mg-doped MBG nanoparticles have reliable bioactivity with high anticancer efficiency, thus representing a promising multifunctional candidate for cancer therapy. [252][253][254] Ca 2+ in MBG nanospheres has been shown to induce transient receptor potential (TRP) channels and calcium-sensing receptor (CaSR) on tumor cells, which resulted in modulation of the Calpain-1-Bcl-2-Caspase-3 signaling pathway to targeted inhibit tumor growth without significant toxicity on normal cells. [122] It was also shown that dendritic MBG nanospheres incorporating anticancer drugs could improve the antitumor efficacy and minimize its systemic toxicity.…”

Section: Biomolecular Mechanisms Underlying Anticancer Effects Of Mbgsmentioning

confidence: 99%

Mesoporous Bioactive Glasses in Cancer Diagnosis and Therapy: Stimuli‐Responsive, Toxicity, Immunogenicity, and Clinical Translation

et al. 2021

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Cancer is one of the top life‐threatening dangers to the human survival, accounting for over 10 million deaths per year. Bioactive glasses have developed dramatically since their discovery 50 years ago, with applications that include therapeutics as well as diagnostics. A new system within the bioactive glass family, mesoporous bioactive glasses (MBGs), has evolved into a multifunctional platform, thanks to MBGs easy‐to‐functionalize nature and tailorable textural properties—surface area, pore size, and pore volume. Although MBGs have yet to meet their potential in tumor treatment and imaging in practice, recently research has shed light on the distinguished MBGs capabilities as promising theranostic systems for cancer imaging and therapy. This review presents research progress in the field of MBG applications in cancer diagnosis and therapy, including synthesis of MBGs, mechanistic overview of MBGs application in tumor diagnosis and drug monitoring, applications of MBGs in cancer therapy ( particularly, targeted delivery and stimuli‐responsive nanoplatforms), and immunological profile of MBG‐based nanodevices in reference to the development of novel cancer therapeutics.

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Section: Biomolecular Mechanisms Underlying Anticancer Effects Of Mbgsmentioning

confidence: 99%

Mesoporous Bioactive Glasses in Cancer Diagnosis and Therapy: Stimuli‐Responsive, Toxicity, Immunogenicity, and Clinical Translation

et al. 2021

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“…When compared to the double layer-coated sample, no considerable mass loss was seen in the Mg alloy after immersion in 3 and 7 days compared to ≈2700 Ohm•cm 2 in the presence of FBS in DMEM. However, after 7 days, a significant shift was detected in the sample with CS-BG coating [72]. Bakhsheshi-Rad et al [73] investigated the corrosion and antibacterial performance of Mg-Zn-Ca alloy coated with CS nanofibers containing silver sulfadiazine (AgSD) multiwall carbon nanotubes (MWCNTs) for bioimplants.…”

Section: Chitosan (Cs) Coated On Mg-based Alloymentioning

confidence: 99%

A Comprehensive Review on Surface Modifications of Biodegradable Magnesium-Based Implant Alloy: Polymer Coatings Opportunities and Challenges

et al. 2021

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The development of biodegradable implants is certainly intriguing, and magnesium and its alloys are considered significant among the various biodegradable materials. Nevertheless, the fast degradation, the generation of a significant amount of hydrogen gas, and the escalation in the pH value of the body solution are significant barriers to their use as an implant material. The appropriate approach is able to solve this issue, resulting in a decrease the rate of Mg degradation, which can be accomplished by alloying, surface adjustment, and mechanical treatment. Surface modification is a practical option because it not only improves corrosion resistance but also prepares a treated surface to improve bone regeneration and cell attachment. Metal coatings, ceramic coatings, and permanent polymers were shown to minimize degradation rates, but inflammation and foreign body responses were also suggested. In contrast to permanent materials, the bioabsorbable polymers normally show the desired biocompatibility. In order to improve the performance of drugs, they are generally encapsulated in biodegradable polymers. This study summarized the most recent advancements in manufacturing polymeric coatings on Mg alloys. The related corrosion resistance enhancement strategies and future potentials are discussed. Ultimately, the major challenges and difficulties are presented with aim of the development of polymer-coated Mg-based implant materials.

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“…In the literature, several studies are presented that used the ELD method to obtain coatings with bioactive glass or composites of glass with hydroxyapatite [181,182], zirconium oxide [18,183], carbon nanotubes [184,185], hyaluronic acid [186], chitosan [187][188][189][190], and alginate [133] on metallic substrates such as titanium [181,182,190,191], titanium alloy Ti-6Al-4V [18,183,189], stainless steel AISI 304 and AISI 316 [133,180,184,185,187,188,[191][192][193], and magnesium [191,194]. For thicknesses up to 50 µm, microwave sintering can be applied, which has proven to be a suitable technique for obtaining coatings without cracks.…”

Section: Other Bioactive Glass Coating Techniquesmentioning

confidence: 99%

Bioactive Glass—An Extensive Study of the Preparation and Coating Methods

Maximov

Crăciun

et al. 2021

Coatings

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Diseases or complications that are caused by bone tissue damage affect millions of patients every year. Orthopedic and dental implants have become important treatment options for replacing and repairing missing or damaged parts of bones and teeth. In order to use a material in the manufacture of implants, the material must meet several requirements, such as mechanical stability, elasticity, biocompatibility, hydrophilicity, corrosion resistance, and non-toxicity. In the 1970s, a biocompatible glassy material called bioactive glass was discovered. At a later time, several glass materials with similar properties were developed. This material has a big potential to be used in formulating medical devices, but its fragility is an important disadvantage. The use of bioactive glasses in the form of coatings on metal substrates allows the combination of the mechanical hardness of the metal and the biocompatibility of the bioactive glass. In this review, an extensive study of the literature was conducted regarding the preparation methods of bioactive glass and the different techniques of coating on various substrates, such as stainless steel, titanium, and their alloys. Furthermore, the main doping agents that can be used to impart special properties to the bioactive glass coatings are described.

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Coating of bioactive glass on magnesium alloys to improve its degradation behavior: Interfacial aspects

Cited by 44 publications

References 105 publications

Mesoporous Bioactive Glasses in Cancer Diagnosis and Therapy: Stimuli‐Responsive, Toxicity, Immunogenicity, and Clinical Translation

Mesoporous Bioactive Glasses in Cancer Diagnosis and Therapy: Stimuli‐Responsive, Toxicity, Immunogenicity, and Clinical Translation

A Comprehensive Review on Surface Modifications of Biodegradable Magnesium-Based Implant Alloy: Polymer Coatings Opportunities and Challenges

Bioactive Glass—An Extensive Study of the Preparation and Coating Methods

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