Cochlear otosclerosis.: Report of a case, with postmortem histologic findings.

Questioning the Relationship between Cochlear Otosclerosis and Sensorineural Hearing Loss: A Quantitative Evaluation of Cochlear Structures in Cases of Otosclerosis and Review of the Literature

“…Several investigators have observed an association between the severity of sensorineural HL and the extent of cochlear endosteal involvement with otosclerosis. 6,8,38,41,42,44,48,49 Some investigators have observed a localized affect of otosclerotic endosteal involvement of the cochlea with atrophy of the adjacent stria vascularis 34,35,39,40,48,50 or hair cell and nerve fiber loss. 50 Others have observed a generalized affect on stria vascularis atrophy 46 and hair cell loss.…”

“…A few cases of profound sensorineural HL have been reported that appear to be related to advanced otosclerosis. 31–35 Benitez and Schuknecht 31 reported the temporal bone findings of an individual with bilateral otosclerosis and progressive HL. In one temporal bone with profound HL, fixation of the stapes and extensive involvement of the cochlear endosteum was observed.…”

“…Holleman and Harrill 34 described the findings from a case of far‐advanced otosclerosis with severe mixed HL bilaterally. Atrophy and fibrosis of the stria vascularis and spiral ligament were most severe in regions where the spiral ligament was in contact with the otosclerotic focus.…”

Cochlear Function after Stapedectomy

“…The cause of deterioration of BC in non-operated ears may be that as a result of the stapes fixation, the inner ear remains inactive, resulting in degeneration of the inner ear [8]. Causse et al [9] in their study on the aetiology of otospongiotic sensorineural losses, they concluded that the proteolytic enzymes relased by the otospongiotic-otosclerotic foci damage the inner ear.…”