Cochliobolus lunatus colonizes potato by adopting different invasion strategies on cultivars: New insights on temperature dependent-virulence

Louis, Bengyella; Waikhom, Sayanika Devi; Jose, Robinson C.; Goyari, Sailendra; Talukdar, Narayan Chandra; Roy, Pranab

doi:10.1016/j.micpath.2015.07.014

Cited by 9 publications

(2 citation statements)

References 31 publications

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“…S15). It has been revealed that haustoria and appressoria are specialized apparatus employed by fungi to adhere and penetrate their hosts and are essential for pathogenic relationships [10,16,17]. The cavities formed due to replacement or digestion of this plant cells were regularly found at the final stage of infection ( Fig.…”

Section: Groupmentioning

confidence: 99%

Investigation on the biotrophic interaction of Ustilago esculenta on Zizania latifolia found in the Indo-Burma biodiversity hotspot

Jose

Goyari

Louis

et al. 2016

Microbial Pathogenesis

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Section: Groupmentioning

confidence: 99%

Investigation on the biotrophic interaction of Ustilago esculenta on Zizania latifolia found in the Indo-Burma biodiversity hotspot

Jose

Goyari

Louis

et al. 2016

Microbial Pathogenesis

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“…Each fungal infection starts with germination of conidia. 21 Because of the ease with which A. terreus colonizes novel niches, one could question whether there exist rare strategies based on morphological changes and adaptability during active invasion of hosts. Nonetheless, the current literature has scanty information on the mechanism by which A. terreus infects plant hosts.…”

Section: Introductionmentioning

confidence: 99%

Invasive <em>Aspergillus terreus</em> morphological transitions and immunoadaptations mediating antifungal resistance

Louis¹,

Yekwa²,

Subhani³

et al. 2017

IDR

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Background and aimsAspergillus terreus Thom is a pathogen of public health and agricultural importance for its seamless abilities to expand its ecological niche. The aim of this study was holistically to investigate A. terreus morphological and immunoadaptations and their implication in antifungal resistance and proliferation during infection.Materials and methodsIn-depth unstructured mining of relevant peer-reviewed literature was performed for A. terreus morphological, immune, resistance, and genetic diversity based on the sequenced calmodulin-like gene.ResultsAccessory conidia and phialidic conidia produced by A. terreus confer discrete anti-fungal resistance that ensures survivability during therapies. Interestingly, by producing unique metabolites such as Asp–melanin and terretonin, A. terreus is capable of hijacking macrophages and scavenging iron, respectively. As such, A. terreus has established a rare mechanism to mitigate phagocytosis and swing the interaction dynamics in favor of its proliferation and survival in hosts.ConclusionIt is further unraveled that besides A. terreus genetic diversity, morphological, biochemical, and immunologic adaptations associated with conidia germination and discharge of chemical signals during infection enable masking of the host defense as an integral part of its strategy to survive and rapidly colonize hosts.

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Cochliobolus lunatus down-regulates proteome at late stage of colonization and transiently alters StNPR1 expression in Solanum tuberosum L.

et al. 2016

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Cochliobolus lunatus abundantly produces four-celled conidia at high temperatures (>30 °C) and under suitable conditions; the fungus colonizes potato (Solanum tuberosum L.) cultivars by adopting different invasion strategies at the microscopic level. Long-lasting defence during infection requires an upsurge in proteome changes particularly pathogenesis-related proteins chiefly under the control of nonexpresser of pathogenesis-related proteins. In order to gain molecular insights, we profiled the changes in proteome and potato nonexpresser of pathogenesis-related proteins (StNPR1) during the infection process. It is found that C. lunatus significantly (P < 0.05) suppressed the host functional proteome by 96 h after infection (hai), principally, affecting the expression of ribulose bisphosphate carboxylase enzyme, plastidic aldolase enzyme, alcohol dehydrogenase 2 and photosystem II protein prior to the formation of brown-to-black leaf spot disease. Strongest host response was observed at 24 hai hallmarked by 307 differentially expressed peptide spots concurring with the active phase of production of penetrating hyphae. Additionally, C. lunatus differentially down-regulated StNPR1 transcript by 8.19 fold by 24 hai. This study is the first to elucidate that C. lunatus transiently down-regulates the expression of StNPR1 at the onset of infection, and as a whole, infection negatively affects the expression of proteome components involved in photosynthesis, carbon fixation and light assimilation. This study contributes towards better understanding of the mechanism underlining the invasion strategies of C. lunatus.

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Cochliobolus lunatus colonizes potato by adopting different invasion strategies on cultivars: New insights on temperature dependent-virulence

Cited by 9 publications

References 31 publications

Investigation on the biotrophic interaction of Ustilago esculenta on Zizania latifolia found in the Indo-Burma biodiversity hotspot

Investigation on the biotrophic interaction of Ustilago esculenta on Zizania latifolia found in the Indo-Burma biodiversity hotspot

Invasive <em>Aspergillus terreus</em> morphological transitions and immunoadaptations mediating antifungal resistance

Cochliobolus lunatus down-regulates proteome at late stage of colonization and transiently alters StNPR1 expression in Solanum tuberosum L.

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