Coding Rate and Duration of Vocalizations of the Frog,<i>Xenopus laevis</i>

Zornik, Erik; Yamaguchi, Ayako

doi:10.1523/jneurosci.2450-12.2012

Cited by 21 publications

(26 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…More recent studies identified a population of vocal premotor neurons in X. laevis DTAM (fast trill neurons, FTNs) with phase-locked spikes preceding each fast trill CAP (Zornik and Yamaguchi, 2012). FTNs exhibit a long-lasting depolarization (LLD) during spiking that coincides with fictive fast trill and with the DTAM LFP wave.…”

Section: Discussion Divergent Temporal Features Of Songs Are Supportementioning

confidence: 99%

“…A local field potential (LFP) wave recorded from DTAM coincides with fast trill and is NMDA receptor dependent (Zornik et al, 2010). Taken together, available evidence suggests that in X. laevis, DTAM neurons drive the LFP wave and control call duration and period (Zornik and Yamaguchi, 2012).…”

Section: Introductionmentioning

confidence: 88%

“…In X. laevis, intracellular recordings in synaptically isolated FTNs reveal rhythmic oscillations in response to NMDA that are similar in duration and period to LLDs recorded during fictive calling (Zornik and Yamaguchi, 2012). Intrinsic cellular properties of FTNs could thus allow them to act as network pacemakers and contribute to fast trill duration and period.…”

Section: Intrinsic Cellular Contributions: Ion Channels and Membrane mentioning

confidence: 93%

“…CAPs were recorded with an extracellular suction electrode placed on the posterior rootlet of cranial nerve IX-X (laryngeal nerve) that contains the axons of the laryngeal motor neurons (Simpson et al, 1986). To elicit a fictive motor pattern on the laryngeal nerve, serotonin (Sigma) was bath applied to the recording dish to a final concentration of 30 or 60 μmol l −1 (Zornik and Yamaguchi, 2012). The signal from the nerve was amplified ×1000 (Model 1700, A-M Systems, Carlsborg, WA, USA) and band-pass filtered (10 Hz to 5 kHz), digitized at 10 or 20 kHz (Digidata 1400A, Molecular Devices, Sunnyvale, CA, USA), and recorded on a personal computer.…”

Section: In Vitro Brain Preparationmentioning

confidence: 99%

“…2A). Neurons in DTAM monosynaptically excite LMN motor neurons that produce vocal patterns (Zornik and Kelley, 2008;Yamaguchi et al, 2008;Zornik et al, 2010;Zornik and Yamaguchi, 2012). A local field potential (LFP) wave recorded from DTAM coincides with fast trill and is NMDA receptor dependent (Zornik et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Evolution of vocal patterns: tuning hindbrain circuits during species divergence

Barkan

Zornik

Kelley

2016

Journal of Experimental Biology

View full text Add to dashboard Cite

The neural circuits underlying divergent courtship behaviors of closely related species provide a framework for insight into the evolution of motor patterns. In frogs, male advertisement calls serve as unique species identifiers and females prefer conspecific to heterospecific calls. Advertisement calls of three relatively recently (∼8.5 Mya) diverged species -Xenopus laevis, X. petersii and X. victorianusinclude rapid trains of sound pulses (fast trills). We show that while fast trills are similar in pulse rate (∼60 pulses s) across the three species, they differ in call duration and period (time from the onset of one call to the onset of the following call). Previous studies of call production in X. laevis used an isolated brain preparation in which the laryngeal nerve produces compound action potentials that correspond to the advertisement call pattern (fictive calling). Here, we show that serotonin evokes fictive calling in X. petersii and X. victorianus as it does in X. laevis. As in X. laevis, fictive fast trill in X. petersii and X. victorianus is accompanied by an N-methyl-D-aspartate receptordependent local field potential wave in a rostral hindbrain nucleus, DTAM. Across the three species, wave duration and period are strongly correlated with species-specific fast trill duration and period, respectively. When DTAM is isolated from the more rostral forebrain and midbrain and/or more caudal laryngeal motor nucleus, the wave persists at species-typical durations and periods. Thus, intrinsic differences within DTAM could be responsible for the evolutionary divergence of call patterns across these related species.

show abstract

Section: Discussion Divergent Temporal Features Of Songs Are Supportementioning

confidence: 99%

Section: Introductionmentioning

confidence: 88%

Section: Intrinsic Cellular Contributions: Ion Channels and Membrane mentioning

confidence: 93%

Section: In Vitro Brain Preparationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Evolution of vocal patterns: tuning hindbrain circuits during species divergence

Barkan

Zornik

Kelley

2016

Journal of Experimental Biology

View full text Add to dashboard Cite

show abstract

Inhibitory and modulatory inputs to the vocal central pattern generator of a teleost fish

Rosner

Rohmann

Bass

et al. 2018

J of Comparative Neurology

View full text Add to dashboard Cite

Vocalization is a behavioral feature that is shared among multiple vertebrate lineages, including fish. The temporal patterning of vocal communication signals is set, in part, by central pattern generators (CPGs). Toadfishes are well‐established models for CPG coding of vocalization at the hindbrain level. The vocal CPG comprises three topographically separate nuclei: pre‐pacemaker, pacemaker, motor. While the connectivity between these nuclei is well understood, their neurochemical profile remains largely unexplored. The highly vocal Gulf toadfish, Opsanus beta, has been the subject of previous behavioral, neuroanatomical and neurophysiological studies. Combining transneuronal neurobiotin‐labeling with immunohistochemistry, we map the distribution of inhibitory neurotransmitters and neuromodulators along with gap junctions in the vocal CPG of this species. Dense GABAergic and glycinergic label is found throughout the CPG, with labeled somata immediately adjacent to or within CPG nuclei, including a distinct subset of pacemaker neurons co‐labeled with neurobiotin and glycine. Neurobiotin‐labeled motor and pacemaker neurons are densely co‐labeled with the gap junction protein connexin 35/36, supporting the hypothesis that transneuronal neurobiotin‐labeling occurs, at least in part, via gap junction coupling. Serotonergic and catecholaminergic label is also robust within the entire vocal CPG, with additional cholinergic label in pacemaker and prepacemaker nuclei. Likely sources of these putative modulatory inputs are neurons within or immediately adjacent to vocal CPG neurons. Together with prior neurophysiological investigations, the results reveal potential mechanisms for generating multiple classes of social context‐dependent vocalizations with widely divergent temporal and spectral properties.

show abstract

Inspiring song: The role of respiratory circuitry in the evolution of vertebrate vocal behavior

Barkan

Zornik

2020

Developmental Neurobiology

View full text Add to dashboard Cite

Vocalization is a common means of communication across vertebrates, but the evolutionary origins of the neural circuits controlling these behaviors are not clear. Peripheral mechanisms of sound production vary widely: fish produce sounds with a swimbladder or pectoral fins; amphibians, reptiles, and mammalians vocalize using a larynx; birds vocalize with a syrinx. Despite the diversity of vocal effectors across taxa, there are many similarities in the neural circuits underlying the control of these organs. Do similarities in vocal circuit structure and function indicate that vocal behaviors first arose in a single common ancestor, or have similar neural circuits arisen independently multiple times during evolution? In this review, we describe the hindbrain circuits that are involved in vocal production across vertebrates. Given that vocalization depends on respiration in most tetrapods, it is not surprising that vocal and respiratory hindbrain circuits across distantly related species are anatomically intermingled and functionally linked. Such vocal‐respiratory circuit integration supports the hypothesis that vocal evolution involved the expansion and functional diversification of breathing circuits. Recent phylogenetic analyses, however, suggest vocal behaviors arose independently in all major tetrapod clades, indicating that similarities in vocal control circuits are the result of repeated co‐options of respiratory circuits in each lineage. It is currently unknown whether vocal circuits across taxa are made up of homologous neurons, or whether vocal neurons in each lineage arose from developmentally and evolutionarily distinct progenitors. Integrative comparative studies of vocal neurons across brain regions and taxa will be required to distinguish between these two scenarios.

show abstract

Coding Rate and Duration of Vocalizations of the Frog,Xenopus laevis

Cited by 21 publications

References 48 publications

Evolution of vocal patterns: tuning hindbrain circuits during species divergence

Evolution of vocal patterns: tuning hindbrain circuits during species divergence

Inhibitory and modulatory inputs to the vocal central pattern generator of a teleost fish

Inspiring song: The role of respiratory circuitry in the evolution of vertebrate vocal behavior

Contact Info

Product

Resources

About