Coexistence of linear morphea and nodular mucinosis

Linearly distributed indurated plaques on the left arm of an 8‐year‐old girl

“…Linear morphea with mucin deposition occurs only rarely, but several cases have been reported, characteristically in linear forms . The present case also manifested linearly along Blaschko's lines.…”

“…To our knowledge, linear morphea with secondary mucinosis has been reported only in Asian populations . However, the scarcity of cases leads us to be prudent in suggesting that mucinosis in morphea occurs more frequently in Asians.…”

“…The present case also manifested linearly along Blaschko's lines. This manifestation may represent a consequence of mosaicism and signify a tendency for mucin to accumulate along Blaschko's lines …”

“…A recent systematic review on morphea treatment indicated the use of methotrexate and corticosteroids in progressive disease and topical calcipotriene or tacrolimus in cases of limited, inflammatory lesions . Published case reports have indicated a poor treatment response to longterm steroid therapy and to a topical fludroxycortide adhesive preparation for morphea with mucinosis. The present patient did not respond to topical tacrolimus 0.1%.…”

Scleroderma with Nodular Scleroderma

“…Since our case presented with multiple skin-colored papules and plaques, a differential diagnosis that should be considered was localized cutaneous mucinosis, which can be found as a coexisting condition with systemic sclerosis or morphea [24, 25, 26, 27, 28]. However, the diagnosis of localized cutaneous mucinosis should be confirmed by mucin deposition in a skin biopsy.…”