Coffee Consumption Increases the Antioxidant Capacity of Plasma and Has No Effect on the Lipid Profile or Vascular Function in Healthy Adults in a Randomized Controlled Trial

Agudelo-Ochoa, Gloria M; Pulgarín-Zapata, Isabel C; Velásquez-Rodriguez, Claudia M; Duque-Ramírez, Mauricio; Naranjo-Cano, Mauricio; Quintero-Ortiz, Mónica M; Lara-Guzmán, Óscar J.; Muñoz-Durango, Katalina

doi:10.3945/jn.115.224774

Cited by 90 publications

(74 citation statements)

References 45 publications

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“…In a large cross-sectional population-based survey, high coffee consumption was associated with reduced triglyceride levels [22], while in another study moderate coffee consumption was associated with increased triglyceride concentrations in men [23]. In an intervention study, however, coffee consumption did not affect the lipid profile [24]. The inconsistencies observed may partly be related to the differences in the types of coffee consumed.…”

Section: Coffee Consumption Was Not Associated With the Triglyceride-mentioning

confidence: 93%

Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes

Stutz

Ahola

Harjutsalo

et al. 2018

Nutrition, Metabolism and Cardiovascular Diseases

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Section: Coffee Consumption Was Not Associated With the Triglyceride-mentioning

confidence: 93%

Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes

Stutz

Ahola

Harjutsalo

et al. 2018

Nutrition, Metabolism and Cardiovascular Diseases

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“…Chlorogenic acid, one of the most important polyphenols to be found in coffee, has well-documented antioxidant properties and thus may inhibit the destructive effects of free radicals on neurons. The literature has suggested that neuroprotective activity of chlorogenic acid is the basis for further research on its use for therapeutic purposes [70, 75]. The amount of polyphenols in coffee depends on numerous factors, including their content in coffee beans and the method of brewing.…”

Section: Coffee: a Possible Mechanism Of Actionmentioning

confidence: 99%

Can coffee consumption lower the risk of Alzheimer’s disease and Parkinson’s disease? A literature review

Wierzejska¹

2017

aoms

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In light of the fact that the number of elderly citizens in society is steadily increasing, the search for dietary factors which might prolong mental agility is growing in significance. Coffee, together with its main ingredient, caffeine, has been the focus of much attention from various researchers, as data on its beneficial effects on human health continue to accumulate. Most reports indicate that moderate coffee consumption may in fact lower the risk for common neurodegenerative conditions, i.e. Alzheimer’s and Parkinson’s diseases. Regardless, due to their complex pathogenesis as well as methodology of scientific research, the exact impact of coffee consumption remains to be fully elucidated. At present, it seems safe to inform the general public that coffee drinkers need not fear for their health. Possibly, in the future experts will recommend drinking coffee not only to satisfy individual taste preferences but also to decrease age-related mental deterioration.

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“…HCAs may enhance cardiovascular health by exerting blood pressurelowering effects and by acutely improving the endothelial function [89,100,101]. Some studies suggest that chlorogenic acids may cause significant reductions in systolic and diastolic blood pressure [100,102,103], but other studies have instead reported a lack of significant blood pressure reduction [104][105][106]. The differences could be attributed to the antihypertensive effects of chlorogenic acids only occurring in subjects with mild hypertension and not in normotensives [88,107].…”

Section: Health Benefits Related To Intake Of Phenolic Acidsmentioning

confidence: 99%

Factors affecting intake, metabolism and health benefits of phenolic acids: do we understand individual variability?

et al. 2019

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Introduction Phenolic acids are important phenolic compounds widespread in foods, contributing to nutritional and organoleptic properties. Factors affceting individual variability The bioavailability of these compounds depends on their free or conjugated presence in food matrices, which is also affected by food processing. Phenolic acids undergo metabolism by the host and residing intestinal microbiota, which causes conjugations and structural modifications of the compounds. Human responses, metabolite profiles and health responses of phenolics, show considerable individual variation, which is affected by absorption, metabolism and genetic variations of subjects. Opinion A better understanding of the gut-host interplay and microbiome biochemistry is becoming highly relevant in understanding the impact of diet and its constituents. It is common to study metabolism and health benefits separately, with some exceptions; however, it should be preferred that health responders and non-responders are studied in combination with explanatory metabolite profiles and gene variants. This approach could turn interindividual variation from a problem in human research to an asset for research on personalized nutrition.

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Coffee Consumption Increases the Antioxidant Capacity of Plasma and Has No Effect on the Lipid Profile or Vascular Function in Healthy Adults in a Randomized Controlled Trial

Cited by 90 publications

References 45 publications

Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes

Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes

Can coffee consumption lower the risk of Alzheimer’s disease and Parkinson’s disease? A literature review

Factors affecting intake, metabolism and health benefits of phenolic acids: do we understand individual variability?

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