Robust monitoring techniques for perennial crops have become increasingly possible due to technological advances in the area of Remote Sensing (RS), and the products are available through the European Space Agency (ESA) initiative. RS data provides valuable opportunities for detailed assessments of crop conditions at plot level using high spatial, spectral, and temporal resolution. This study addresses the monitoring of coffee at the plot level using RS, analyzing the relationship between the spatio-temporal variability of the Leaf Area Index (LAI) and the crop coefficient (Kc); the Kc being a biophysical variable that integrates the potential hydrological characteristics of an agroecosystem compared to the reference crop. Daily and one-year Kc were estimated using the relation of crop evapotranspiration and reference. ESA Sentinel-2 images were pre-analyzed and atmospherically corrected, and Top-of-the-Atmosphere (TOA) reflections converted to Top-of-the-Canopy (TOC) reflectance. The TOCs resampled at the 10m resolution, and with the angles corresponding to the directional information at the time of the acquisition, the LAI was estimated using the trained neural network available in the Sentinel Application Platform (SNAP). During 75% of the monitored days, Kc ranged between 1.2 and 1.3 and, the LAI analyzed showed high spatial and temporal variability at the plot level. Based on the relationship between the biophysical variables, the LAI variable can substitute the Kc and be used to monitor the water conditions at the production area as well as analyze spatial variability inside that area. Sentinel-2 products could be more useful in monitoring coffee in the farm production area.