Cognitive function at admission predicts amount of gait speed change in geriatric physical rehabilitation

Schaefer, Sydney Y.; Sullivan, Jacklyn M.; Peterson, Daniel S.; Fauth, Elizabeth B.

doi:10.1016/j.rehab.2019.08.004

Cited by 9 publications

(4 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To our knowledge, no predictive models of therapeutic responsiveness include cognitive variables, despite growing evidence that they may explain significant amounts of variance in motor learning [4][5][6]. For example, attention, executive function, and visuospatial memory underlie crucial stages of motor learning and are also among the most common cognitive deficits reported following stroke.…”

Section: Introductionmentioning

confidence: 99%

Generalizing the predictive relationship between 1-month motor skill retention and Rey–Osterrieth Delayed Recall scores from nondemented older adults to individuals with chronic stroke: a short report

VanGilder

Hooyman

Bosch

et al. 2021

J NeuroEngineering Rehabil

Self Cite

View full text Add to dashboard Cite

Motor learning is fundamental to motor rehabilitation outcomes. There is growing evidence from non-neurological populations supporting the role of visuospatial memory function in motor learning, but current predictive models of motor recovery of individuals with stroke generally exclude cognitive measures, thereby overlooking the potential link between motor learning and visuospatial memory. Recent work has demonstrated that a clinical test of visuospatial memory (Rey–Osterrieth Complex Figure Delayed Recall) may predict 1-month skill learning in older adults; however, whether this relationship persists in individuals with chronic stroke remains unknown. The purpose of this short report was to validate previous findings using Rey–Osterrieth Complex Figure Delayed Recall test scores to predict motor learning and determine if this relationship generalized to a set of individuals post-stroke. Two regression models (one including Delayed Recall scores and one without) were trained using data from non-stroke older adults. To determine the extent to which Delayed Recall test scores impacted prediction accuracy of 1-month skill learning in older adults, we used leave-one-out cross-validation to evaluate the prediction error between models. To test if this predictive relationship generalized to individuals with chronic ischemic stroke, we then tested each trained model on an independent stroke dataset. Results indicated that in both stroke and older adult datasets, inclusion of Delayed Recall scores explained significantly more variance of 1-month skill performance than models that included age, education, and baseline motor performance alone. This proof-of-concept suggests that the relationship between delayed visuospatial memory and 1-month motor skill performance generalizes to individuals with chronic stroke, and supports the idea that visuospatial testing may provide prognostic insight into clinical motor rehabilitation outcomes.

show abstract

Section: Introductionmentioning

confidence: 99%

Generalizing the predictive relationship between 1-month motor skill retention and Rey–Osterrieth Delayed Recall scores from nondemented older adults to individuals with chronic stroke: a short report

VanGilder

Hooyman

Bosch

et al. 2021

J NeuroEngineering Rehabil

Self Cite

View full text Add to dashboard Cite

show abstract

“…In contrast, cognitive assessment may be a feasible, brief, and relatively inexpensive tool for gaining insight to an individual's motor learning capacity (see 3 ). For example, global cognitive status has been shown to predict gains in walking speed following standard-of-care physical therapy independent of primary diagnosis, 4 but the relationship between global cognitive measures and clinical upper-extremity outcomes in PD has not been explored. In a recent randomized clinical trial in individuals with mild-to-moderate PD (clinicaltrial.gov registration number NCT02600858), 5 motor practice while "on" dopamine replacement medication (i.e., levodopa) improved 48-hour retention of a functional upper extremity motor task compared to practice "off" dopamine replacement medication.…”

Section: Introductionmentioning

confidence: 99%

Global cognition is related to upper-extremity motor skill retention in individuals with mild-to-moderate Parkinson disease

Lopez-Lennon

et al. 2021

Preprint

Self Cite

View full text Add to dashboard Cite

Background and Purpose: Cognitive impairment has been linked to poor motor learning and rehabilitation outcomes in older adult and stroke populations, but this remains unexplored in individuals with Parkinson disease (PD). The purpose of this secondary data analysis from a recent clinical trial (NCT02600858) was to determine if global cognition was related to nine-day skill retention after upper-extremity motor training in individuals with PD. Methods: Twenty-three participants with idiopathic PD completed three consecutive days of training on an upper-extremity task. For the purposes of the original clinical trial, participants trained either on or off their dopamine replacement medication. Baseline, training, and shorter-term (48-hour) retention data have been previously published. Global cognition was evaluated using the Montreal Cognitive Assessment (MoCA). Participant age, baseline performance, MoCA score, and group (medication on/off) were included in a multivariate linear regression model to predict longer-term (nine day) follow-up performance. Baseline and follow-up performance were assessed for all participants while on their medication. Results: MoCA score was positively related to follow-up performance, such that individuals with better cognition performed better than those with poorer cognition. Participant age, baseline performance, and medication status were unrelated to follow-up performance. Discussion and Conclusions: Results of this secondary analysis align with previous work that suggest cognitive impairment may interfere with motor learning in PD, and that assessing cognition could provide prognostic information about an individuals responsiveness to motor rehabilitation for a number of clinical populations.

show abstract

“…In contrast, cognitive assessment may be a feasible, brief, and relatively inexpensive tool for gaining insight to an individual's motor learning capacity [see ( 12 )]. Global cognitive status has been shown to predict gains in gait speed following standard-of-care physical therapy independent of primary diagnosis ( 13 , 14 ). With respect to PD specifically, physical therapy combined with cognitive training may be more efficacious in improving reactive postural adjustments (i.e., responses to perturbations) and motor symptoms than physical therapy alone ( 15 ).…”

Section: Introductionmentioning

confidence: 99%

Relating Global Cognition With Upper-Extremity Motor Skill Retention in Individuals With Mild-to-Moderate Parkinson's Disease

VanGilder

Lopez-Lennon

Paul

et al. 2021

Front. Rehabilit. Sci.

Self Cite

View full text Add to dashboard Cite

Background and Purpose: Cognition has been linked to rehabilitation outcomes in stroke populations, but this remains unexplored in individuals with Parkinson's disease (PD). The purpose of this secondary data analysis from a recent clinical trial (NCT02600858) was to determine if global cognition was related to skill performance after motor training in individuals with PD.Methods: Twenty-three participants with idiopathic PD completed 3 days of training on an upper-extremity task. For the purposes of the original clinical trial, participants trained either “on” or “off” their dopamine replacement medication. Baseline, training, and 48-h retention data have been previously published. Global cognition was evaluated using the Montreal Cognitive Assessment (MoCA). Linear regression examined whether MoCA score predicted longer-term retention at nine-day follow-up; baseline motor task performance, age, PD severity, depressive symptoms, and group (medication “on”/“off”) were included as covariates. Baseline and follow-up motor task performance were assessed for all participants while “on” their medication.Results: MoCA score was positively related to follow-up motor task performance, such that individuals with better cognition were faster than those with poorer cognition. Baseline task performance, age, PD severity, depressive symptoms, and medication status were unrelated to follow-up performance.Discussion and Conclusions: Results of this secondary analysis align with previous work that suggest cognitive impairment may interfere with motor learning in PD and support the premise that cognitive training prior to or concurrent with motor training may enhance rehabilitative outcomes for individuals with PD. Findings also suggest that assessing cognition in individuals with PD could provide prognostic information about their responsiveness to motor rehabilitation.

show abstract

Cognitive function at admission predicts amount of gait speed change in geriatric physical rehabilitation

Cited by 9 publications

References 11 publications

Generalizing the predictive relationship between 1-month motor skill retention and Rey–Osterrieth Delayed Recall scores from nondemented older adults to individuals with chronic stroke: a short report

Generalizing the predictive relationship between 1-month motor skill retention and Rey–Osterrieth Delayed Recall scores from nondemented older adults to individuals with chronic stroke: a short report

Global cognition is related to upper-extremity motor skill retention in individuals with mild-to-moderate Parkinson disease

Relating Global Cognition With Upper-Extremity Motor Skill Retention in Individuals With Mild-to-Moderate Parkinson's Disease

Contact Info

Product

Resources

About