Coinfección de tuberculosis y candidiasis pulmonar en paciente previamente sana

Abstract

Background: The coexistance among fungal pathogens and tuberculosis pulmonary is a clinical condition that generally occurs in immunosuppressive patients, however, immunocompetent patients may have this condition less frequently. Objective: We report the case of an immunocompetent patient diagnosed with coinfection Mycobacterium tuberculosis and Candida albicans. Case Description: 22-year-old female patient, previously healthy, who presented an episode of cough, massive hemoptysis and fever. Clinical findings and diagnosis: Physical examination was found crakles in left lung. Microbiological testing includes Ziehl Neelsen, culture for mycobacterium, fungal culture in Sabouraud Dextrose Agar medium and serum filamentation. The tests showed Mycobacterium tuberculosis and Candida albicans. Imaging studies included chest radiography, chest CT scan apicograma and high resolution supported the diagnosis. Treatment and Outcome: The patient was treated with anti-tuberculosis and anti-fungal treatment with good clinical evolution. Clinical relevance: Fungal infection and pulmonary tuberculosis is rare in immunocompetent patients should be suspected in abrupt episodes of hemoptysis.

<p>Fungal Isolates of the Respiratory Tract in Symptomatic Patients Hospitalized in Pulmonary Units: A Mycological and Molecular Epidemiologic Study</p>

“…The results of different studies showed that physicians should pay particular attention to fungal co-infection with pulmonary TB. 27,39,40 In a study of Kali and colleagues Candida co-infection was observed in 40% of patients with pulmonary tuberculosis. 39 Also, Denning et al reported that from 21% (United States of America) to 35% (Taiwan, China) of pulmonary tuberculosis patients developed pulmonary cavities and about 22% of these patients developed chronic pulmonary aspergillosis.…”