Colistin-resistant Gram-negative bacteria in Saudi Arabia: A literature review

Assessment of risk factors associated with multidrug-resistant organism infections among patients admitted in a tertiary hospital - a retrospective study

“…Another study revealed that respiratory infections are the most frequent infection associated with MDRO sepsis, followed by urinary infections ( Prado et al, 2022 ). Previous studies in Saudi Arabia investigated the association of risk factors and MDRO, however, mostly in a group of organisms such as gram negative bacteria ( Al Hamdan et al, 2022 ) or Acinetobacter species ( Al Bshabshe et al, 2016 ) or in a single organism such as acinetobacter baumanni ( Almaghrabi et al, 2018 ) or investigating bacteria resistant to a certain antibiotic ( Al Mayahi et al, 2019 , Alqasim, 2021 ). Of note, studies covering all MRDOs types in Saudi Arabia were dated back to 2014 and 2015 ( Mwanri and AlSaleh, 2014 , Baig et al, 2015 ).…”

Antibacterial and anti-biofilm activity of plumbagin against multi-drug resistant clinical bacterial isolates

“…This resistance, mediated by extended-spectrum β-lactamase (ESBL), 25 has now increased due to the worldwide dissemination of the specific E. coli clone, E. coli ST131. 26 In an attempt to tackle this resistance issue, more powerful agents, such as carbapenems and polymyxins, have recently been relaunched as alternatives to inactive antibiotics. However, carbapenems suffer from poor absorbability, and cause pruritis, hepatotoxicity, diarrhea, vomiting, and nausea.…”

Capacity Utilization Assessment Using Discrete-Event Simulation: Case Study of a High-Density Crowd Visiting the Holy Rawda in the City of Madinah

“…A high-density crowd is a challenging problem that has been addressed in literature from different aspects [1]. Saudi Arabia faces high-density crowd problems, especially at the two holy mosques that Muslims from all over the world visit to perform the Islamic rituals [2]. Due to the importance of these rituals, Vision 2030 sets a specific goal to enable 30 million pilgrims achieve a transformative faith experience [3] through improving their experience of hospitality, space, safety and other services.…”