Collapsing glomerulopathy in a patient with mixed connective tissue disease

Chamarthi, Gajapathiraju; Clapp, William L.; Gopal, Saraswathi

doi:10.1007/s13730-020-00542-1

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…The steps typically involved in the definitive diagnosis of collapsing glomerulopathy; 1. The clinical evaluation helps identify patients with symptoms consistent with collapsing glomerulopathy, such as proteinuria, nephrotic syndrome, hypertension, and renal insufficiency (7). 2.…”

Section: Pathologic Features Of Collapsing Fsgsmentioning

confidence: 99%

Collapsing glomerulopathy; a review on current studies

Baradaran,

Daneii,

Imankhan

et al. 2023

J Prev Epidemiol

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Collapsing glomerulopathy is a rare and serious disease that is characterized by a rapid deterioration of kidney function and heavy proteinuria. This disease is a variant of focal segmental glomerulosclerosis (FSGS). The disease is more serious than other types of FSGS, with high risks of renal failure and poor prognosis. Collapsing glomerulopathy is often resistant to immunosuppressive therapy and can rapidly result in renal failure, making diagnosing and managing this disease an enormous challenge.

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Section: Pathologic Features Of Collapsing Fsgsmentioning

confidence: 99%

Collapsing glomerulopathy; a review on current studies

Baradaran,

Daneii,

Imankhan

et al. 2023

J Prev Epidemiol

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“…It is mediated by immune complexes and it is characterized by subepithelial granular deposition of IgG and complement leading to podocyte injury (1). Collapsing variant of focal segmental glomerulosclerosis (cFSGS) is diagnosed in light microscopy by the presence of at least one glomerulus tuff with segmental or global collapse and podocyte hypertrophy or hyperplasia (2). Although both entities present with NS, unlike MN, cFSGS has worse prognosis and usually fails to respond to therapy, evolves with rapid deterioration of kidney function and progresses to end stage kidney disease (3).…”

Section: Introductionmentioning

confidence: 99%

Membranous nephropathy with collapse in a HIV negative patient; a case report with a 34-month follow-up

et al. 2022

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Membranous nephropathy (MN) is a common cause of nephrotic syndrome (NS) in nondiabetic adults. Collapsing nephropathy (CN) is a morphological pattern that is usually classified as a variant of focal segmental glomerulosclerosis (cFSGS). The simultaneous presence of both MN and CN is rare and their combination usually foresees an unfavorable outcome. Herein, we describe a case report of a patient with PLA2 R-associated MN with collapse, its treatment and clinical course.

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