Collection of analytical data for benzodiazepines and benzophenones

The solute molecule—Rigid or partially flexible? calculation of benzodiazepineR F values as an example

“…Benzodiazepines have also often been the subject of QSRR studies and many published data, obtained by well-respected authors, are available [2][3][4][5].…”

“…The retention data used in this investigation were taken from the literature [3], because the authors had graphically corrected RF values to those obtained with reference materials, and they were thus expected to be exact.…”

Screening for Drugs of Abuse (II): Cannabinoids, Lysergic Acid Diethylamide, Buprenorphine, Methadone, Barbiturates, Benzodiazepines and other Drugs

“…The clinical pharmacokinetics of the benzodiazepines have been recently reviewed by Busto et al 198 Detection methods A large volume of analytical data for the benzodiazepines and their related benzophenones was collated by Japp et a/. 203 Some differences in basic chemical characteristics are summarized in Table 5. …”

Rapid and simple analysis of oxazolobenzodiazepine drugs in sera by wide-bore capillary gas chromatography with nitrogen-phosphorus detection using on-column methylation

“…Various methods for the determination of benzodiazepines in biological materials have been reported. Analytical methods for underivatized oxazolobenzodiazepines and other benzodiazepines include thin-layer chromatography (TLC) [2,3], high-performance (HP) TLC [4], gas chromatography (GC) [3,[5][6][7], GC-mass spectrometry (MS) [3,5,[7][8][9], high-performance liquid chromatography (HPLC) [3,10,11], and immunoassays [12]. However, simultaneous determination of methylated oxazolobenzodiazepine drugs by GC or GC/MS has not been reported to our knowledge.…”