Color Doppler Ultrasound in Diagnosis and Assessment of Carotid Body Tumors: Comparison with Computed Tomography Angiography

Jin, Zhanqiang; He, Wen; Wu, Depei; Lin, Mei-Ying; Jiang, Hua-Tang

doi:10.1016/j.ultrasmedbio.2016.04.007

Cited by 17 publications

(9 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…18 Recently, 3DVR has been correlated with blood loss during resection. 19 In the present study, CBT patients were grouped by 3DVR in quartiles, demonstrating no association with less HRQoL. This finding could be because 3DVR is preferably used as a postoperative outcome predictor.…”

Section: Discussionmentioning

confidence: 43%

“…This finding could be because 3DVR is preferably used as a postoperative outcome predictor. 19,20 Due to the rarity of these neoplasms, the recruitment of patients is an important limitation, even in tertiary medical centers in endemic regions as our institution which is a referral center in Mexico City with 15 cases per year. Another limitation is that our study represents a specific and localized geographic area, and might not represent the perception of other places; however, this is one of the few studies aiming to evaluate the QoL of patients with CBTs.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Assessment of health-related quality of life in patients prior to carotid body tumor resection

et al. 2019

View full text Add to dashboard Cite

Background Carotid body tumors represent approximately 0.5% of the total head and neck tumors, and the most common presentation form is an asymptomatic cervical mass. Despite of being most of them asymptomatic the quality of life could be impacted; however, the literature remains silent about this matter. The Short Form 36 (SF-36) is a health-related quality of life (HRQoL) instrument that includes eight domains to assess physical and emotional function in different diseases. The aim of this study was to compare HRQoL in preoperative patients with carotid body tumor and a control paired group. The secondary objective was to compare HRQoL between carotid body tumor patients according to the volume tumor and Shamblin classification. Methods A cross-sectional study that included 23 patients diagnosed with carotid body tumor prior to resection and 23 control patients paired by age and gender was conducted from January 2017 to December 2018. The SF-36 questionnaire was applied in 46 patients. Three-dimensional volume reconstruction and estimation (3DVR) was obtained from a preoperative computed tomography angiography (CTA). Descriptive statistical analysis was performed for demographics and categorical variables were reported by frequencies and percentages. Continuous variables were summarized using median with interquartile ranges (IQR) with 95% confidence interval (CI) and were compared. Differences between medians were analyzed with the Mann–Whitney U test and all statistical tests were two-sided. Results In the carotid body tumor group, the mean age was 55 years, females were more frequently affected 19 (83%). Shamblin I was identified in 9% of patients, Shamblin II in 52% and Shamblin III in 39%. Carotid body tumor laterality were 57% right, 34% left and 9% bilateral tumors. The eight domains that comprise the SF-36 questionnaire were statistically significant when compared to the control group. Conclusion Significant differences were found in all SF-36 domains in carotid body tumor patients in comparison to control subjects, confirming that this neoplasm has negative impact in the general HRQoL.

show abstract

Section: Discussionmentioning

confidence: 43%

Section: Discussionmentioning

confidence: 99%

Assessment of health-related quality of life in patients prior to carotid body tumor resection

et al. 2019

View full text Add to dashboard Cite

show abstract

“…The presence of numerous, tortuous vessels with turbulent, low-resistance flow is highly indicative of a PGL (13,14) . Jin et al (15) showed a statistically significant difference between the Doppler ultrasound appearance of neck tumors vascularity of nerve sheath tumors and carotid PGLs to the advantage of the latter, as well as low RI values for these masses. A comparative analysis of the vascular flow in both external carotid arteries additionally aids the diagnosis, as the majority of PGL patients show a decreased RI in the ipsilateral external carotid artery, due to the presence of arteriovenous fistulas within the lesion (13,16) .…”

Section: Discussionmentioning

confidence: 99%

Doppler ultrasound appearance of neck tumors

et al. 2018

View full text Add to dashboard Cite

Aim: The purpose of this study was the evaluation of the sonographic appearance of neck tumors and determining the features useful in differential diagnosis. Material and method: The studied group consisted of 57 patients: 16 patients with carotid body tumors, 9 patients with neurogenic tumors, 8 patients with venous anomalies, 12 patients with neck cysts, 6 patients with lipomas, 5 patients with extracranial carotid artery aneurysms and 1 with a laryngocele. Results: All carotid paragangliomas were located within the carotid bifurcation and demonstrated rich low-resistance vascular flow, with higher maximum velocity and lower flow resistance parameters registered in the ipsilateral external carotid artery. In 7 out of 9 cases, neurogenic tumors were homogeneous, and in the remaining 2 cases – heterogeneous. Four schwannomas were hypervascular or showed moderate vascularity, and the rest of neurogenic tumors were hypovascular or avascular, with symmetrical maximum velocity and resistance values of carotid blood flow. Apart from one branchial cleft cyst with multiple fine internal acoustic reflexes, all other neck cysts were anechoic and avascular, and presented with posterior acoustic enhancement. The laryngocele presented as a well-demarcated, hypoechoic, homogeneous lesion located in the immediate proximity of the larynx, without signs of internal vascular flow. Lipomas were well-demarcated, homogeneous, hypoechoic tumors with regular margins, without signs of internal vascular flow. Venous malformations presented as irregular, hypoechoic spaces with venous blood flow, easily compressed by the probe. Extracranial carotid artery aneurysms were hypoechoic, well-defined spaces, which presented with slow internal, turbulent flow on Doppler study, and showed continuity with the carotid artery. Conclusions: Doppler ultrasound allows to visualize features characteristic for certain neck tumors. Solid or cystic structure, echogenicity, localization, as well as internal flow signals and vascularity pattern create a combination of ultrasound findings helpful in the differential diagnosis of lesions such as paragangliomas, venous malformations, neurogenic tumors, aneurysms, cysts and laryngoceles.

show abstract

“…Carotid ultrasound is widely accepted as a first non-invasive tool to establish the diagnosis of CBTs. However, CT of neck angiography adds more detailed information, and reveals the relationship between lesions and adjacent arteries, as well as the involvement of the skull base [11]. In other words, it helps assess the tumor size and surgical (Shamblin) type more accurately (Fig.…”

Section: Discussionmentioning

confidence: 99%

Carotid Body Tumor With Malignant Behavior in a Patient in His Eighth Decade

2017

View full text Add to dashboard Cite

Carotid body tumors (CBTs) are rare neoplasms with rare malignant potential. These tumors are usually parasympathetic ganglia-derived lesions which located in the neck at the bifurcation of the external and internal carotid arteries. In contrary to sympathetic-derived tumors, they are often non-secretory. However, about 5% of these tumors may still secrete some of the catecholamine-related compounds. Most of these lesions are diagnosed in the third to fifth decades of life, with more cases revealed during autopsy examinations. Although it is considered a disease of middle age, elderly people are not immune. We report a case of an elderly patient in his eighth decade, who presented with a mass-like lesion in the right side of his neck during routine medical examination. Imaging study showed an enhancing mass in the carotid artery bifurcation with pressure effect and lymphadenopathy. The patient underwent surgery and tumor was removed uneventfully. The pathology report later confirmed ovalshaped cells with positive neuroendocrine markers consistent with carotid body paraganglioma. We believe these tumors are overlooked and yet may be missed without proper medical examination. We report this case for two reasons, being a very rare tumor with malignant potential in an elderly patient and to raise the awareness among medical practitioners.

show abstract

Color Doppler Ultrasound in Diagnosis and Assessment of Carotid Body Tumors: Comparison with Computed Tomography Angiography

Cited by 17 publications

References 17 publications

Assessment of health-related quality of life in patients prior to carotid body tumor resection

Assessment of health-related quality of life in patients prior to carotid body tumor resection

Doppler ultrasound appearance of neck tumors

Carotid Body Tumor With Malignant Behavior in a Patient in His Eighth Decade

Contact Info

Product

Resources

About