2024
DOI: 10.3390/cancers16081530
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Colorectal Cancer: Epidemiology, Risk Factors, and Prevention

Gholamreza Roshandel,
Fatemeh Ghasemi-Kebria,
Reza Malekzadeh

Abstract: Colorectal cancer (CRC) is the third most common cancer and the second most common cause of cancer mortality worldwide. There are disparities in the epidemiology of CRC across different populations, most probably due to differences in exposure to lifestyle and environmental factors related to CRC. Prevention is the most effective method for controlling CRC. Primary prevention includes determining and avoiding modifiable risk factors (e.g., alcohol consumption, smoking, and dietary factors) as well as increasin… Show more

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Cited by 26 publications
(1 citation statement)
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“…Sulindac has been shown to be effective in reducing the risk of colorectal adenomatous polyps, precursors of colorectal cancer. Aspirin has also shown a preventive effect on colorectal cancer, especially in patients with a family history of the disease [ 127 , 128 , 129 , 130 , 131 ].…”
Section: Discussionmentioning
confidence: 99%
“…Sulindac has been shown to be effective in reducing the risk of colorectal adenomatous polyps, precursors of colorectal cancer. Aspirin has also shown a preventive effect on colorectal cancer, especially in patients with a family history of the disease [ 127 , 128 , 129 , 130 , 131 ].…”
Section: Discussionmentioning
confidence: 99%