Colorectal cancer survival trends in Norway 1958–1997

Angell-Andersen, E.; Tretli, Steinar; Coleman, Michel P; Langmark, Frøydis; Grotmol, Tom

doi:10.1016/j.ejca.2003.09.034

Cited by 49 publications

(55 citation statements)

References 21 publications

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“…Genomic instability comprises chromosomal as well as microsatellite instability [16]. years in sporadic CRC [19]. Similar to sporadic cancer, neoplastic progression in ulcerative colitis is thought to occur in a stepwise manner, but generally from flat mucosa and not from adenomas as for sporadic carcinomas.…”

Section: Carcinogenesis Of Crc In Ibdmentioning

confidence: 99%

Relationship between clinical parameters and the colitis-colorectal cancer interval in a cohort of patients with colorectal cancer in inflammatory bowel disease

Brackmann

Andersen

Aamodt

et al. 2009

Scandinavian Journal of Gastroenterology

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Section: Carcinogenesis Of Crc In Ibdmentioning

confidence: 99%

Relationship between clinical parameters and the colitis-colorectal cancer interval in a cohort of patients with colorectal cancer in inflammatory bowel disease

Brackmann

Andersen

Aamodt

et al. 2009

Scandinavian Journal of Gastroenterology

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“…CRC is also the second leading cause ofcancer death in Europe [3,4]. Over the last decades, mortality rates from CRC have declined [4,5], but this improvement in survival has been less evident in the older age groups [4,6,7].…”

Section: Introductionmentioning

confidence: 99%

Frailty Is an Independent Predictor of Survival in Older Patients With Colorectal Cancer

et al. 2014

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Background. Colorectal cancer (CRC) is prevalent in the older population. Geriatric assessment (GA) has previously been found to predict treatment tolerance and postoperative complications in older cancer patients. The aim of this study was to explore whether GA also predicts 1-year and 5-year survival after CRC surgery in older patients and to compare the predictive power of GA with that of established prognostic factors such as TNM classification of malignant tumors (TNM) stage and age. Materials and Methods. A cohort of 178 CRC patients aged 70 and older were followed prospectively. All patients went through elective surgery, and GA was performed presurgery. The GA resulted in patients being divided into two groups: frail or nonfrail. All patients were followed for 5 years or until death. Data were analyzed by Kaplan-Meier plots and the Cox proportional hazards model.

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“…In the larger Dutch study, the reported 2-year survival was 82% after TME and short-course RT, and 81.8% after TME surgery [16]. A more aggressive surgical approach to local recurrence and distant metastasis may have contributed to these results [11]. …”

Section: Discussionmentioning

confidence: 99%

“…Improvement in survival rates may be attributed to several factors: peri- and postoperative mortality has declined (table 2) [10]; the introduction of antibiotic prophylaxis, improved anesthetic surveillance and refined surgical techniques may also have played an important role [11], and standard and extended radical operations involving radicular ligation of regional vessels have been introduced along with the monitoring of postoperative complications and mortality [8]. …”

Section: Discussionmentioning

confidence: 99%

Improved Outcome of Patients with Colorectal Cancer: The Ljubljana University Medical Centre Experience

et al. 2008

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Background/Aims: Analysis of outcome in patients undergoing resection for colorectal carcinoma. Methods: Between 1/1/1991 and 31/12/2000, 1,478 patients with a colon and rectal carcinoma underwent a potentially curative resection. The results were analyzed for two groups of patients given different treatment regimens during two consecutive 5-year periods. The 5-year survival rate was estimated by the Kaplan-Meier method. Results: Over a period of 10 years, 1,478 patients were treated by resection. The 5-year survival rate for R0 resected patients with stage I and stage III colon cancer in the period 1996–2000 was significantly higher than for patients operated on between 1991 and 1995 (stage I: 86 vs. 70%; stage III: 58 vs. 40%). Similarly, the 5-year survival rate for R0 resected patients with stage III rectal cancer between 1996 and 2000 was significantly better than that for patients operated on during the early period (58 vs. 31%). Conclusions: Patients who underwent R0 resection for colorectal cancer during the period 1995–2000 showed a significantly improved 5-year survival rate compared to those operated on between 1991 and 1995. Improved survival in these patients is to a great extent attributable to improvements in clinical practice combining surgery and adjuvant therapy.

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Colorectal cancer survival trends in Norway 1958–1997

Cited by 49 publications

References 21 publications

Relationship between clinical parameters and the colitis-colorectal cancer interval in a cohort of patients with colorectal cancer in inflammatory bowel disease

Relationship between clinical parameters and the colitis-colorectal cancer interval in a cohort of patients with colorectal cancer in inflammatory bowel disease

Frailty Is an Independent Predictor of Survival in Older Patients With Colorectal Cancer

Improved Outcome of Patients with Colorectal Cancer: The Ljubljana University Medical Centre Experience

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