Colorectal Neoplasm in Asymptomatic Average-risk Koreans: The KASID Prospective Multicenter Colonoscopy Survey

Park, Hye Won; Byeon, Jeong Sik; Yang, Suk Kyun; Kim, Hyun Soo; Kim, Won Ho; Tae, Kim Hyung; Park, Dong; Kim, Young Ho; Kim, Hyo Jong; Lee, Moon Sung; Chung, Kwon; Jung, Sung Ae; Jeen, Yoon Tae; Choi, Jai Hyun; Choi, Hwang; Choi, Kyu Yong; Han, Dong Soo; Song, Jae Seok

doi:10.5009/gnl.2009.3.1.35

Cited by 59 publications

(58 citation statements)

References 20 publications

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“…Our estimates of the prevalence of colorectal adenomas are consistent with previous studies based on more selected and smaller screening samples (7,11). In one study, the prevalence of colorectal adenomas among average risk asymptomatic Koreans 50 years of age or older were 39.9% and 23.0% among men and women, respectively (7), whereas in another study, the prevalence among Korean men 40 to 69 years of age was 36.3% (11).…”

Section: Discussionsupporting

confidence: 89%

“…These participants had no symptoms of colorectal disease, no personal history of colorectal cancer, polyps, or inflammatory bowel disease, no colon examination within the last 10 years, no previous colonic surgery, and no family history of colorectal polyps. Similarly, a multicenter colonoscopy survey conducted in 2003 to 2004 among 11 university hospitals in Korea found prevalence rates of 33.3% and 2.2% for colorectal adenomas and advanced adenomas, respectively (7). Although it is assumed that the incidence of colorectal adenomas is increasing in proportion to colorectal cancer rates, there is limited data on recent adenoma trends in Korea (8).…”

Section: Introductionmentioning

confidence: 99%

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The Prevalence of Colorectal Adenomas in Asymptomatic Korean Men and Women

Yang

Rampal

Sung

et al. 2014

Cancer Epidemiology, Biomarkers &Amp; Prevention

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Background: Colorectal cancer incidence is rapidly rising in many Asian countries, with rates approaching those of Western countries. This study aimed to evaluate the prevalence and trends of colorectal adenomas by age, sex, and risk strata in asymptomatic Koreans.Methods: Cross-sectional study of 19,372 consecutive participants aged 20 to 79 years undergoing screening colonoscopy at the Center for Health Promotion of the Samsung Medical Center in Korea from January 2006 to June 2009.Results: Among participants at average risk, those without a history of colorectal polyps or a family history of colorectal cancer, the prevalence of colorectal adenomas and advanced adenomas were 34.5% and 3.1%, respectively, in men and 20.0% and 1.6%, respectively, in women. The prevalence of adenomas increased with age in both men and women, with a more marked increase for advanced adenoma. Participants with a family history of colorectal cancer or with a history of colorectal polyps had significantly higher prevalence of adenomas compared with participants of average risk (36.9% vs. 26.9%; age-and sex-adjusted prevalence ratio ¼ 1.16; 95% confidence interval, 1.09-1.22). The prevalence of adenomas increased annually in both men and women.Conclusions: In this large study of asymptomatic Korean men and women participating in a colonoscopy screening program, the prevalence of colorectal adenomas was comparable and possibly higher than previously reported in Western countries.Impact: Cost-effectiveness studies investigating the optimal age for starting colonoscopy screening and etiological studies to identify the reasons for the increasing trend in colorectal adenomas in Koreans are needed. Cancer Epidemiol Biomarkers Prev; 23(3); 499-507. Ó2014 AACR.

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Section: Discussionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

The Prevalence of Colorectal Adenomas in Asymptomatic Korean Men and Women

Yang

Rampal

Sung

et al. 2014

Cancer Epidemiology, Biomarkers &Amp; Prevention

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“…The incidence of colonic adenoma has increased rapidly in Korea. In a recent multicenter study, the prevalence rate of colonic neoplasm in asymptomatic Korean adults was 33.2%, which was similar in Western countries (2,3). However, patients with removed adenoma remain at high risk of developing new adenomas or cancer in the subsequent years, which justified follow-up colonoscopy (4).…”

Section: Introductionmentioning

confidence: 71%

Clinical and endoscopic predictors of colorectal adenoma recurrence after colon polypectomy

Jang¹,

Kim²,

Jung³

et al. 2013

Turk J Gastroenterol

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“…The purpose of the screening program was to promote health through early detection of chronic diseases and their risk factors. Such programs are popular in Korea (10). In addition, in Korea, the Industrial Safety and Health Law requires employees to participate in annual or biennial health examinations.…”

Section: Study Populationmentioning

confidence: 99%

Impact of Body Mass Index on the Risk of Colorectal Adenoma in a Metabolically Healthy Population

et al. 2013

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Metabolically healthy obese (MHO) states exist that seem to be protected from cardiovascular risks. Although obesity is a risk factor for colorectal adenoma (CRA), there has yet to be any study of the risks of CRA in MHO individuals. In this study, we compared CRA prevalence in MHO individuals versus metabolically healthy individuals who were normal in weight. This cross-sectional study involved 18,085 Korean adults (39.1 AE 6.7 years) who had a health checkup including a colonoscopy. High-risk CRA was defined as any adenoma over 1 cm, 3 or more adenomas, adenoma with a villous component, or high-grade dysplasia. Multinomial logistic regression models were used to measure the associations between body mass index (BMI) and the risk of low-risk and highrisk CRA. Low-risk and high-risk CRA were present in 9.3% and 1.4% of the study population, respectively. After adjusting for age, sex, smoking, drinking, exercise, family history of colorectal cancer, education, and use of analgesic and aspirin, compared with normal healthy individuals, the prevalence of low-risk and high-risk CRA was increased in MHO individuals [OR ¼ 1.44; 95% confidence interval (CI), 1.23-1.69 and OR ¼ 1.62; 95% CI, 1.09-2.41, respectively]. In fully adjusted models, the prevalence of low-risk and high-risk CRA was associated with increasing categories of BMI in a dose-response manner (P for trend < 0.001 and 0.01, respectively). Thus, excess body weight, even in the absence of a metabolic unhealthy state, was found to be positively associated with increased presence of CRAs. Cancer Res; 73(13); 4020-7. Ó2013 AACR.

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Colorectal Neoplasm in Asymptomatic Average-risk Koreans: The KASID Prospective Multicenter Colonoscopy Survey

Cited by 59 publications

References 20 publications

The Prevalence of Colorectal Adenomas in Asymptomatic Korean Men and Women

The Prevalence of Colorectal Adenomas in Asymptomatic Korean Men and Women

Clinical and endoscopic predictors of colorectal adenoma recurrence after colon polypectomy

Impact of Body Mass Index on the Risk of Colorectal Adenoma in a Metabolically Healthy Population

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